United States Post Office (Burbank, California) is an architecturally significant working post office in Downtown Burbank, California, operated by the United States Postal Service (USPS). It was added to the National Register of Historic Places (NRHP) on January 11, 1985.

Gilbert Stanley Underwood designed the building, which was built under the Works Progress Administration (WPA). Design and construction began in 1937, the cornerstone was laid January 21, 1938, and the building was dedicated on April 30, 1938. In December of that year a $1900 federal art commission was announced. The opportunity to decorate the Burbank post office building was open to residents of California and Nevada. The building lobby is decorated with two murals painted by Barse Miller depicting the economy of Burbank.

The first Burbank post office opened in 1898, located 95 rods north of the Southern Pacific station. In 1921 the second Burbank post office was on block six of Burbank.

The Glenoaks Post Office in Burbank closed in 2014, with Downtown Burbank absorbing its functions.