Downtown Greensboro Historic District is a national historic district located at Greensboro, Guilford County, North Carolina. When first listed, the district encompassed 96 contributing buildings in the central business district of Greensboro. The commercial buildings were built between about 1885 and the 1930s in a variety of popular architectural styles including Italianate and Art Deco. Located in the district is the separately listed Jefferson Standard Building. Other notable buildings include the Vanstory Building (c. 1885), Kress Building (1929), Woolworth's (c. 1929), Efrid's Department Store (c. 1930), Montgomery Ward (1936), the Carolina Theatre (1927), Center Theatre (1948), the former Belk Building (1939), Ellis Stone/Thalhimer's Department Store (1949-1950), and the former American Exchange National Bank Building (1920). The Woolworth's store is notable as the site of the Greensboro sit-ins of 1960.

It was listed on the National Register of Historic Places in 1982, with a reevaluation in 2003, and boundary adjustments in 2023. The most recent changes included adding city and country government buildings completed by 1975.

• 
  Piedmont Building, 2015
• 
  Dixie Fire Insurance Company Building, 2015
• 
  Center Theater & Porter Drug Store, 2015
• 
  American Exchange National Bank, 2015
• 
  Carolina Theater, 2015
• 
  Greensboro Passenger Depot, 2015

Media related to Downtown Greensboro Historic District at Wikimedia Commons