Earth City is an unincorporated commercial area located in St. Louis County, Missouri, United States, along Interstate 70, near the Missouri River. It is bounded by the city of Bridgeton on the east and north, the city of Maryland Heights to the south, and the Missouri River to the west. It is also near Lambert International Airport. Earth City is notable as being home to the headquarters of the Save-A-Lot grocery chain and a major UPS shipping hub. As of 2010, the community has no permanent residents.

Earth City is the home to the corporate headquarters of Spectrum Brands (Pet, Home and Garden division).

Earth City is home to the former Rams Park, the training facility and offices of the St. Louis Rams during the Rams' time in St. Louis from 1995 to 2015. The facility is now known as the Lou Fusz Athletic Training Center and is home to the Lou Fusz Soccer Club.

• Earth City Levee District
• Northwest Chamber of Commerce