Echigo-Ōshima Station (越後大島駅, Echigo-Ōshima-eki) is a railway station in the village of Sekikawa, Niigata Prefecture, Japan, operated by East Japan Railway Company (JR East).

Echigo-Ōshima Station is served by the Yonesaka Line, and is located 83.5 rail kilometers from the terminus of the line at Yonezawa Station.

The station has one ground-level side platform serving a single bi-directional track. The station is unattended.

Echigo-Ōshima Station opened on 10 August 1931. The station was absorbed into the JR East network upon the privatization of JNR on 1 April 1987.

• National Route 113

• List of railway stations in Japan

• JR East Station information (in Japanese)