The Edmond J. Safra Synagogue is an Orthodox Jewish synagogue, under construction, located at 2085 Ocean Parkway, Brooklyn, in New York City, New York, United States. The synagogue is one of several that are eponymous with Edmond J. Safra, a former banker and philanthropist, partially or fully funded by the Edmond J. Safra Foundation.

Founded in 2005, the congregation practices in the Sephardic rite and is composed of participants of Sephardic and Middle Eastern descent, including immigrants from: Syria, Lebanon, Egypt, Morocco, Israel, Yemen, and Turkey, along with their descendants.

The congregation is led by Rabbi Eli Mansour and Rabbi Nathan Escava.

The synagogue building was designed over a period of ten years, by Building Studio Architects, and as of December 2023, was under construction. The limestone and granite building recalls Brooklyn's grand civic buildings from the 1920's-30's, with Art Deco and neo-Classical proportions and details completed in the Moderne style. The synagogue is expected to be completed in 2024.