Effia-Kwesimintsim Municipal District is one of the fourteen districts in Western Region, Ghana. Originally it was formerly part of the then-larger Sekondi Takoradi Metropolitan District on 29 February 2008, until the western part of the district was split off to create Effia-Kwesimintsim Municipal District on 15 March 2018; thus the remaining part has been retained as Sekondi Takoradi Metropolitan District. The municipality is located in the southeast part of Western Region and has Kwesimintsim as its capital town.

• "Districts of Ghana". Statoids.

4°54′52.2″N 1°47′15.36″W / 4.914500°N 1.7876000°W / 4.914500; -1.7876000