Erasmuskloof is a suburb in the east of the city of Pretoria, South Africa. It borders the suburbs of Constantia Park, Waterkloof Glen, Moreleta Park, Elardus Park, Erasmus Park, Erasmusrand and Waterkloof Glen.

Erasmuskloof is positioned near the N1 highway and major shopping malls Menlyn Park, Menlyn Retail Park, Menlyn Maine, coffee bars, restaurants, cafés and Castle Walk Shopping Centre.