Frankfurt am Main Konstablerwache station (German: Bahnhof Frankfurt am Main Konstablerwache) is a major train station and metro station at the Konstablerwache square in the city centre of Frankfurt am Main, Germany.

As of 2019, with 98,000 passengers per day, Konstablerwache station is the second busiest rapid transit station in Frankfurt after Frankfurt Central Station, and a major hub for commuter transport in the Frankfurt/Rhine-Main region. It is served by eight S-Bahn lines (S1–S6, S8, S9), four U-Bahn lines (U4-U7), two tram lines (12, 18) and two bus lines (30, 36).

The station is situated under the Konstablerwache at the eastern end of the Zeil, Frankfurt's main shopping street. Hauptwache station, the third busiest station in Frankfurt, is located at the western end of the Zeil.

At the start of the 20th century, Konstablerwache was one of the key hubs of Frankfurt trams. The first part of the U-Bahn opened in 1968 and the B Line through Konstablerwache opened on 26 May 1974. In 1983, the S-Bahn City Tunnel was extended under the Zeil from Hauptwache to Konstablerwache. In 1986, the inauguration of operations through the Zeil tunnels was completed when the U6 and U7 services commenced on the C Line of the U-Bahn.

In 1978, tram operations were discontinued at Konstablerwache when the tram tracks along the Zeil were closed. In 1999, the first new tram line since U-Bahn construction began was opened along Kurt Schumacher and Konrad Adenauer streets. The route is served by lines 12 and 18.

As in the case of Hauptwache station, Konstablerwache has three underground levels. The first, level B, is a large distribution level. In addition to giving access to the platforms, it serves as a shopping mall and a pedestrian underpass. Below this is a section of a north-south road tunnel that was never completed.

One level below, on level C, is the three-platform station for the U-Bahn B Line, served by the U4 and U5. The western track is used by west-bound U5 trains towards Frankfurt Hauptbahnhof, the middle track is used by west-bound U4 trains towards Bockenheimer Warte, via the Hauptbahnhof. The eastern track is used by both U5 towards Preungesheim and U4 towards Seckbacher Landstraße.

Underneath, on level D, are the platforms for the S-Bahn and U-Bahn C Line (U6 and U7) through the City Tunnel. The S-Bahn runs on the inner two tracks and the U-Bahn on the outer two, with two island platforms to allow cross-platform interchange between them.

In 2010 the French artist group CitéCréation [de] and its subsidiary CreativeStadt from Potsdam created a Trompe-l'œil in the metro station, titled "Reise in Raum und Zeit" (journey through space and time). The artwork was unveiled on 11 June 2010 to mark the 50th anniversary of the town twinning between Frankfurt and Lyon, and shows different scenes from Frankfurt and Lyon.