The Frankland River is a major perennial river located in the north-west region of Tasmania, Australia.

Formed by the confluence of the Horton and Lindsay rivers, the Frankland River rises in the Sumac Forest Reserve and flows generally west by north. The Frankland River reaches its mouth in remote country east of the settlement of Arthur River where it empties into the Arthur River. The river descends 142 metres (466 ft) over its 41-kilometre (25 mi) course.

The river draws its name from George Frankland, an English surveyor and Surveyor-General of Van Diemen's Land between 1827 and 1838.

• Rivers of Tasmania