Güer Aike Department is a department in Santa Cruz Province, Argentina. It has a population of 113,267 and an area of 33,841 km. The seat of the department is in Río Gallegos which also has the majority of the population with 97,742. Veintiocho de Noviembre has the next largest population with 6,145 inhabitants. The name means 'large camp' in the aonikenk (or 'tehuelche') language of southern Patagonia.

• El Turbio
• Julia Dufour
• Mina 3
• Río Gallegos
• Río Turbio
• Rospentek
• Veintiocho de Noviembre
• Güer Aike
• Camusu Aike

• Instituto Nacional de Estadísticas y Censos, INDEC

51°37′24″S 69°12′59″W / 51.62333°S 69.21639°W / -51.62333; -69.21639