The Gallup Commercial Historic District is a historic district which was listed on the National Register of Historic Places in 2016.

It includes "the largest concentration of historic commercial buildings in Gallup", in one- and two-story stores along U.S. Route 66 and W. Coal Ave.in Gallup. It includes 65 contributing buildings, one contributing structure, and a contributing object, as well as 26 non-contributing buildings.

The district also includes seven properties already separately listed on the National Register:

• Rex Hotel
• Old U.S. Post Office
• Palace Lodge
• El Morro Theater
• Grand Hotel (Ricca's Mercantile)
• White Café, and
• Chief Theater.

The listing newly adds 58 contributing buildings and adds 38 acres (15 ha) to the National Register (excluding the area of the seven previously listed properties).