Gambrills refers to two neighboring places in Anne Arundel County, Maryland, United States, located in the Annapolis metro area: the unincorporated community of Gambrills, and the Gambrills census-designated place (CDP). The area was named after Augustine Gambrill, plantation owner. The CDP covers an expansive range that falls within the communities of Crofton, Waugh Chapel, and Odenton. It also borders Davidsonville, Crownsville, Millersville, and Prince George's County, Maryland.

The original village of Gambrills was located on Annapolis Road, 2 miles (3 km) southeast of the center of Odenton. Today, it is an unincorporated, census-designated place. It is the location of Whites Hall Farm, the birthplace and boyhood home of Maryland native Johns Hopkins.

Historical population

Census	Pop.	Note	%±
2010	2,800		—
2020	3,034		8.4%
2021 (est.)	3,185		5.0%
U.S. Decennial Census

Unincorporated Gambrills has an estimated population of 3,185 as of 2021. In 2022, the population of the CDP was 2,837. The median-income of residents was $140,238.

Gambrills is served by routes 3, 32, and MARC, the Maryland commuter rail service. There is a MARC station in neighboring Odenton. Gambrills is located along Maryland Route 175 (Annapolis Road), and extends south and southeast around the town of Crofton.

Gambrills is the site of two large power centers adjacent to one another: Waugh Chapel Towne Centre (650,000 sq. ft.) part of a 1.2 million square foot mixed-use development, and the Village at Waugh Chapel (357,000 square feet).

The area is served by the following schools:

• Crofton Elementary School (Crofton, Maryland)
• Crofton Woods Elementary School (Crofton, Maryland)
• Crofton Meadows Elementary School (Crofton, Maryland)
• Millersville Elementary School (Millersville, Maryland)
• Nantucket Elementary School ((Crofton, Maryland))
• Four Seasons Elementary School (Gambrills, Maryland)
• Odenton Elementary School (Odenton, Maryland)
• Waugh Chapel Elementary School (Odenton, Maryland)
• School of the Incarnation (Gambrills, Maryland)
• Crofton Middle School (Gambrills, Maryland)
• Arundel Middle School (Odenton, Maryland)
• Old Mill Middle School South (Millersville)
• Arundel High School (Gambrills, Maryland)
• Crofton High School (Gambrills, Maryland)
• Old Mill High School (Millersville)

• Johns Hopkins – businessman involved in the building of the B&O Railroad, founded Johns Hopkins University and Johns Hopkins Hospital was born in Gambrills.