Gare du Midi (French) or Zuidstation (Dutch) is a rapid transit station in Brussels, Belgium, consisting of both a metro station (on the southern segment of lines 2 and 6) and a premetro (underground tram) station (serving lines 4 and 10 on the North–South Axis between Brussels-North railway station and Albert premetro station).

The metro station opened on 2 October 1988 as the southern terminus of line 2 from Simonis. Line 2 has since been extended beyond Gare du Midi/Zuidstation to Clemenceau in 1993, Delacroix in 2006, and Gare de l'Ouest/Weststation in 2009. Since 3 December 1993, the station has also accommodated North–South Axis premetro services at separate platforms, with cross-platform interchange between metro and premetro in both directions. Then, following the reorganisation of the Brussels Metro on 4 April 2009, it is served by lines 2, 3, 4 and 6. Line 3 was disbanded in 2024 and replaced by the new line 10.

The metro station is located under Brussels-South railway station, the busiest station in Belgium, and the only Brussels stop for international high-speed rail services Eurostar (including the former Thalys) and TGV.

The South Tower, the tallest building in Belgium, stands in front of the station's main exit (the crossroad of the Avenue Fonsny/Fonsnylaan and the Rue Couverte/Bedektestraat) and houses the Belgian Federal Pensions Service (FPS).

• Transport in Brussels
• History of Brussels

• Media related to Brussels Midi station (metro) at Wikimedia Commons