The General James Mitchell Varnum House is an historic house at 57 Peirce Street in East Greenwich, Rhode Island. The 2+1⁄2-story wood-frame house was built in 1773 for James Mitchell Varnum, who later served as a general in the Continental Army during the American Revolutionary War. It is five bays wide, with two interior brick chimneys. Its main entry is sheltered by a portico supported by fluted Ionic columns and pilasters. A 19th-century addition extends from the rear of the main block. Notable later residents of the house include George A. Brayton, who served as Chief Justice of the Rhode Island Supreme Court. The house was purchased in 1939 by the Varnum Continentals, and has since served as a museum.

The house was listed on the National Register of Historic Places in 1971.

• National Register of Historic Places listings in Kent County, Rhode Island

• Varnum House Museum
• Historic American Buildings Survey (HABS) No. RI-56, "General James M. Varnum House, 57 Pierce Street, East Greenwich, Kent County, RI", 1 photo, supplemental material

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  Varnum House in 1887
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  Varnum House in 2018