Gillotts School is a coeducational secondary school with academy status in Henley-on-Thames, Oxfordshire, England. The school is sited on a 33 acre verdant campus on the edge of Henley, incorporating a large Victorian manor house and two of its associated cottages. There are extensive playing fields, as well as areas of grass, trees and woodland.

Gillotts was established as a girls' boarding school in parkland on the fringe of Henley-on-Thames in 1950, under founding headmistress Betty Barford. Gillotts became a coeducational comprehensive school in 1960. The current headteacher is Catharine Darnton, former headteachers include Malcolm White, and David H W Grubb as well as Mr Lockyer. Lotto multi-millionaire winner Gerry Cannings taught history at the school from 1976 until 1983.

Gillotts school has three houses: Darwin, Pankhurst, and Orwell (named after Charles Darwin, Emmeline Pankhurst, and George Orwell).

• Alec Hepburn Professional Exeter Chiefs and England Rugby Union rugby player
• Simon Kernick (born 1966), crime novelist
• Johnny Robinson, 2011 X-Factor finalist
• Marcus du Sautoy (born 1965), Simonyi Professor for the Public Understanding of Science and a Professor of Mathematics at the University of Oxford
• Andrew Tristem (born 1968), author and journalist

51°31′31″N 0°55′18″W / 51.5252°N 0.9216°W / 51.5252; -0.9216