Glenade Lough (Irish: Loch Ghleann Éada, meaning 'lake of the glen of jealousy'), locally known as Glenade Lake, is a freshwater lake in the northwest of Ireland. It is located in north County Leitrim in the Glenade Valley.

Glenade Lough is situated between the Dartry Mountains to the west and the Arroo Mountain range to the east. The lake is located about 9 kilometres (6 mi) northwest of Manorhamilton and 12 km (7 mi) south of Kinlough. It is 1.6 km (1 mi) long from northwest to southeast and covers an area of 0.74 square kilometres (0.3 sq mi).

Glenade Lough is fed by a number of streams entering at the lake's northern end. The lake drains south into the Bonet River.

Fish species in Glenade Lough include roach, perch, pike and the critically endangered European eel. The lake is also home to the white-clawed crayfish, another endangered species. Glenade Lough and its immediate surroundings were designated a Special Area of Conservation in 1997.

The water quality was reported to be satisfactory c. 2001 – c. 2003 with a mesotrophic rating. The ecology of Glenade Lough, and other County Leitrim waterways, is threatened by curly waterweed, zebra mussel, and freshwater clam invasive species.

Glenade Lough is a site for the legendary beast (or cryptid) the Dobhar-chú, a very large otter-like creature believed to inhabit the lake. A gravestone in a nearby cemetery commemorates the alleged killing of a local woman by a dobhar-chú in 1722.

• List of loughs in Ireland