Gmina Grybów is a rural gmina (administrative district) in Nowy Sącz County, Lesser Poland Voivodeship, in southern Poland. Its seat is the town of Grybów, although the town is not part of the territory of the gmina.

The gmina covers an area of 153.01 square kilometres (59.1 sq mi), and as of 2006 its total population is 22,436.

Gmina Grybów contains the villages and settlements of Biała Niżna, Binczarowa, Chodorowa, Cieniawa, Florynka, Gródek, Kąclowa, Krużlowa Niżna, Krużlowa Wyżna, Polna, Ptaszkowa, Siołkowa, Stara Wieś, Stróże, Wawrzka and Wyskitna.

Gmina Grybów is bordered by the town of Grybów and by the gminas of Bobowa, Chełmiec, Gorlice, Kamionka Wielka, Korzenna, Krynica-Zdrój, Łabowa, Łużna, Ropa and Uście Gorlickie.

• Polish official population figures 2006