Grabowno Wielkie [ɡraˈbɔvnɔ ˈvjɛlkʲɛ] is a village in the administrative district of Gmina Twardogóra, within Oleśnica County, Lower Silesian Voivodeship, in south-western Poland. Prior to 1945 it was in Germany.

It lies approximately 4 kilometres (2 mi) south-west of Twardogóra, 17 kilometres (11 mi) north of Oleśnica, and 37 kilometres (23 mi) north-east of the regional capital Wrocław. Grabowno Wielkie is an important railroad junction, where the connection from Wroclaw divides into two lines - towards Ostrów Wielkopolski, and towards Krotoszyn.