Guabiruba is a municipality situated in the state of Santa Catarina, Brazil, with an estimated 24,382 inhabitants. It is located in 27°05′09″ S and 48°58′52″ W and 60 m above sea level. It was colonized principally by people from Baden, Germany.

Guabiruba is known as "Pelznickelland".

27°05′09″S 48°58′52″W / 27.0858°S 48.9811°W / -27.0858; -48.9811