Hadley House and Grist Mill is a historic home and grist mill located near Pittsboro, Chatham County, North Carolina. The house was built about 1858, and is a two-story, three bay by two bay, Greek Revival style frame dwelling. It has a one-story rear ell and one-bay front porch, and sits on a stone foundation. The mill dates to 1885, and is a three-story frame structure on a stone foundation. It has an exterior iron mill wheel measuring 16 feet in diameter. The mill continued in operation until the 1930s. Also on the property are the contributing two-story frame smokehouse, foundation stones for the original detached kitchen and quarters, and archaeological remains.

It was listed on the National Register of Historic Places in 1980.