Haydarpaşa is a locality within the Kadıköy and Üsküdar districts on the Asian part of Istanbul, Turkey. Haydarpaşa is named after Ottoman Vizier Haydar Pasha. The place, on the coast of Sea of Marmara, borders to Harem in the northwest and Kadıköy in the southeast. It is a historical area with almost solely public buildings. Haydarpaşa is administered by the Mukhtars of Rasımpaşa and Osmanağa parishes (Turkish: Mahallesi Muhtarı).

Internationally known structures around the area are the Haydarpaşa Terminal, Port of Haydarpaşa and the Selimiye Barracks in adjacent Harem.

Following public structures, built in the 19th century or early 20th century during the Ottoman era, are found in Haydarpaşa:

• Haydarpaşa Numune Hastanesi (Haydarpaşa Paragon Hospital)
• GATA Haydarpaşa Eğitim Hastanesi (Haydarpaşa Hospital of Gülhane Military Medical Academy)
• Dr Siyami Ersek Hospital — A renowned hospital for cardiology
• Marmara University, Faculty of Medicine, Haydarpaşa Campus. The building was used by Haydarpaşa Lisesi (Haydarpaşa High School) from 1933 through 1983
• Haydarpaşa Technical High schools

There is/was a Jewish school in Haydarpaşa. Circa the 1920s, due to a decline in the quantity and quality of French education (as laws had changed that required education to be given in a list of languages - Turkish and others protected by the Treaty of Lausanne, on which French was not on), the student population declined from 150 to 50.

• Haydarpaşa Terminal — One of the two main railway terminals of Istanbul serving the railway net in Anatolia
• Port of Haydarpaşa — Biggest container terminal in Istanbul
• Haydarpaşa Ferry boat terminal — Passenger ferries connecting trains to Sirkeci and Karaköy on the European side, and Kadıköy

• Haydarpaşa Cemetery — Historical British military and civilian cemetery

• Selimiye Barracks — Historical barracks, where Florence Nightingale served between 1854 and 1856
• Karacaahmet Cemetery — Biggest cemetery in Turkey