Herisau railway station (German: Bahnhof Herisau) is a railway station in Herisau, in the Swiss canton of Appenzell Ausserrhoden. It is an intermediate station on the 1,435 mm (4 ft 8+1⁄2 in) standard gauge Bodensee–Toggenburg line of Südostbahn and the 1,000 mm (3 ft 3+3⁄8 in) metre gauge Gossau–Wasserauen line of Appenzell Railways. Both companies have separate tracks and facilities, separated by Bahnhofplatz.

Herisau serves both the east–west 1,435 mm (4 ft 8+1⁄2 in) standard gauge Bodensee–Toggenburg line of Südostbahn (SOB) and the north–south 1,000 mm (3 ft 3+3⁄8 in) metre gauge Gossau–Wasserauen line of Appenzell Railways (AB). SOB has two platforms serving three tracks (Nos. 1–3) on the north side of Bahnhofplatz. AB is similarly situated, with two platforms serving tracks 11–13 south of Bahnhofplatz.

A major project is underway to improve access to the station and redevelop parts of the site. This project will shift the Appenzell Railways tracks and platforms a short distance to the south, permitting the construction of a new bus loading area off Bahnhofplatz. Besides affording greater capacity, this loading area will be handicap-accessible. Traffic congestion will be further reduced by the construction of a roundabout at the intersection of Bahnhofplatz and Bahnhofstrasse, just west of the station. Construction work began in January 2021; it is estimated that the entire project will be complete by 2028.

As of the December 2023 timetable change, the following services stop at Herisau (most regional services are part of the Bodensee S-Bahn):

• IR Voralpen-Express: hourly service over the Bodensee–Toggenburg line between Lucerne and St. Gallen.
• RegioExpress RE1: hourly service over the Bodensee–Toggenburg line to Konstanz.
• St. Gallen S-Bahn:
  • S2 / S4: half-hourly service between Wattwil and Altstätten SG via St. Gallen and hourly service to Rapperswil, Sargans, and Nesslau-Neu St. Johann.
  • S23: half-hourly service over the Gossau–Wasserauen line between Gossau SG and Wasserauen.
  • S81: hourly service over the Bodensee–Toggenburg line to St. Gallen.

The S2 and S4 combine for half-hourly service between Wattwil and Altstätten SG; the various services on the Bodensee–Toggenburg line provide one train approximately every 11 minutes between Herisau and St. Gallen.

• "Bahnhofplatz Mit Bushof Herisau" (PDF) (in German). Herisau. 17 March 2017. Retrieved 18 April 2021.

• Media related to Herisau railway station at Wikimedia Commons
• Herisau railway station – SBB