The Holmul River (Spanish: Río Holmul) is a river in northeastern Guatemala that flows through the Petén Basin region in the departamento (department) of El Petén towards the border with Belize. A number of significant pre-Columbian Maya sites lie along or near the course of this waterway, including Tikal, Nakum, Holmul, Naranjo, Yaxha and Witzna.