Hon-Isahaya Station (本諫早駅, Hon-Isahaya-eki) is a passenger railway station in located in the city of Isahaya, Nagasaki. It is operated by third-sector railway company Shimabara Railway.

The station is served by the Shimabara Railway Line and is located 1.5 km from the starting point of the line at Isahaya.

The station is on the ground level with two opposing side platforms for two tracks, plus two sidings on the Isahaya side. The platforms are connected by a level crossing within the premises. When trains are not switching, both up and down trains stop at the platform on the station building side. As Isahaya Station only has one platform and one track, the siding is used for storing vehicles. There is a two-story station building on the north side of the platform. It The station is staffed. There is an automatic ticket machine in the waiting room inside the station building.

1	■ ■ Shimabara Railway Line	for Shimabara and Shimabarakō
2	■ ■Shimabara Railway Line	for Isahaya

• 
  Platforms looking towards Saiwai
• 
  Siding

The station was opened on 20 June 1911. In December 1989 the existing station building was completed.

In fiscal 2018, there were a total of 213,436 boarding passengers, given a daily average of 584 passengers.

The Station is in the central area of Isahaya City.

• Isahaya City Office
• Isahaya Post Office
• Isahaya High School
• Isahaya Legal Affairs Bureau
• Isahaya City Library
• Isahaya Park

• List of railway stations in Japan

• Nagasaki statistical yearbook (Nagasaki prefectural office statistics section,Japanese)

Media related to Hon-Isahaya Station at Wikimedia Commons

• Shimabara Railway Official Site (in Japanese)