Hopkins High School is a public high school located in Minnetonka, Minnesota, United States. Hopkins High School is part of the Hopkins School District 270.

In the 1970s, there were two high schools in the district: Dwight D. Eisenhower Senior High School, named for the former general and U.S. president and Charles A. Lindbergh Senior High School named for the Minnesota native and famed aviator. In 1982, Hopkins closed Eisenhower High School, located in a 1950s-era building along Highway 7, and renamed the remaining school Hopkins Senior High School. The older building was converted to a community center and theater. Later part of the building was converted for use as an elementary school.

Hopkins High School was Minnesota's first National School of Excellence. In 1996, Hopkins was the only high school in Minnesota honored for overall excellence in Redbook's "America's Best High Schools" project. The Language Arts Department has been named a "Center for Excellence" by the National Council of Teachers of English in recognition of the writing program. The Community Involvement program is one of six in the nation honored by the IBM Corporation and U.S. News & World Report. U.S. News & World Report also ranked the school #628 in their 2012 list of best public high schools in America.

Hopkins is also home to KHOP-TV which produces both weekly shows and cable programming, a school dance program called the Royelles, a Hip-Hop dance team named Deeply Royal, as well as a Student Government and school newspaper.

Hopkins High School is a member of the Lake Conference of the Minnesota State High School League.

This article's list of alumni may not follow Wikipedia's verifiability policy. Please improve this article by removing names that do not have independent reliable sources showing they merit inclusion in this article AND are alumni, or by incorporating the relevant publications into the body of the article through appropriate citations. (February 2019)

• Stefon Leron Alexander – rapper/musician known as P.O.S and member of Doomtree collective
• Travis Boyd – NHL player for the Utah Hockey Club
• Paige Bueckers – basketball player, UConn Huskies and multiple USA national youth teams
• Amir Coffey – basketball player, Minnesota Golden Gophers, Los Angeles Clippers.
• Nia Coffey - basketball player, Northwestern Wildcats, Atlanta Dream
• Courtney Dauwalter – ultramarathon runner
• Andrew Dawson – Grammy Award-winning music producer and engineer
• Joseph Fahnbulleh – Liberian-American sprinter, attended the 2020 Tokyo Olympics and placed 5th in the men's 200m final.
• LeRoy Gardner III – national champion wrestler, (2001 and 2003)
• Joan Guetschow – Olympic athlete (1985 graduate)
• Holly Henry – Musician and former The Voice (U.S. TV series) contestant
• Kris Humphries – NBA basketball player, Atlanta Hawks, Washington Wizards, New Jersey Nets
• Alexander Johnson – figure skater
• Kathryn Johnson – U.S. rugby player, 2016 Olympics Rugby 7s
• Jo Ling Kent – news reporter
• Brian Klaas – Political scientist and author
• Joe Klecker – professional runner and 2021 Olympian
• Jim Korn – NHL player (1980–1990)
• Garrott Kuzzy – 2010 Olympic cross country skier
• Lazerbeak – rapper/musician and member of Doomtree collective
• Michael Lehan – football player, Cleveland Browns cornerback (2003–2005), Miami Dolphins (2006–2008)
• Karen McGrane – content strategist and website accessibility advocate
• Mike Mictlan – rapper/musician and member of Doomtree collective
• Zeke Nnaji – basketball player, Arizona Wildcats, Denver Nuggets
• Cecil Otter – rapper/musician and member of Doomtree collective
• Jeffrey Lee Parson – apprehended by FBI for creating MSBlast. B computer virus in 2003
• Ryan Schreiber – founded Pitchfork Media and Pitchfork Music Festival
• Steve Simon - politician
• Sims (rapper) – rapper/musician and member of Doomtree collective
• Todd Sklar – filmmaker, Box Elder, Awful Nice
• Dave Snuggerud – Captain MN Gophers NCAA Runner Up 1989. Drafted #1 overall in the 1988 NHL Supplemental Draft. NHL player. Buffalo Sabres, San Jose Sharks, Philadelphia Flyers (1989–1993)
• Nadine Strossen – president of American Civil Liberties Union (1991–2008). Hopkins debater.
• Paper Tiger – rapper/musician and member of Doomtree collective
• Royce White – basketball player (Houston Rockets) and political candidate