House at 1413 Lafayette St. is a historic home located at Lexington, Lafayette County, Missouri. It was built about 1840, and is a 1+1⁄2-story, side passage plan, Greek Revival style brick I-house. It has a one-story rear ell. It features an impressive entry with transom and sidelights, a parapet gable roof, and segmental arched windows on the rear wing.

It was listed on the National Register of Historic Places in 1999.