Huxford is an unincorporated community in Escambia County, Alabama, United States. Huxford is located near Alabama State Route 21, 13.7 miles (22.0 km) north of Atmore. Huxford had a post office until November 5, 2011; it still has its own ZIP code, 36543. Huxford is located along the route of the Federal Road. Huxford has a population of 197 people.