Huyton Quarry railway station opened in 1830 as part of the Liverpool and Manchester Railway, but Holt suggests it was originally known as the "station at the bottom of Whiston Incline" being renamed Huyton Quarry sometime after 1838. Either way it was one of the earliest passenger railway stations in the world. The station was closed by BR on 15 September 1958.

In 2014, an electrical switching site was constructed in the vicinity as part of the Manchester - Liverpool (via Earlestown) section of the NW electrification schemes.

Preceding station		Disused railways		Following station
Huyton		Liverpool and Manchester Railway		Whiston