Interstate 10 (I-10) in the US state of New Mexico is a 164.264-mile (264.357 km) long route of the United States Interstate Highway System. I-10 traverses southern New Mexico through Hidalgo, Grant, Luna, and Doña Ana counties. The interstate travels west–east from the Arizona state line to the interchange with I-25 in Las Cruces, and then travels north–south to the Texas state line. US Route 80 in New Mexico (US 80) was replaced by I-10.

I-10 enters Hidalgo County, New Mexico from Cochise County, Arizona as a four lane divided highway. The highway travels east through rural southwest New Mexico, passing between Steins Mountain and Attorney Mountain, part of the Peloncillo Mountains, before passing by the ghost town of Steins. Continuing east, the northern terminus of New Mexico State Road 80 (NM 80) is intersected, serving Rodeo, followed by NM 338. Passing Lee Peak, the highway turns southeast, entering Lordsburg. US 70 is intersected in town, and becomes concurrent with the highway as it continues east past the Lordsburg Municipal Airport, before exiting the town. Near the Grant County line, the highway bypasses the ghost town called Shakespeare. Entering Grant County, the highway continues southeast then northeast after intersecting NM 146. The highway passes over the Continental Divide on the Grant–Luna county line. Continuing east, the highway intersects the city of Deming and the highway becomes concurrent with US 180 as the three highways continue east. The highway enters Doña Ana County as it approaches Las Cruces. US 70 exits the highway as it enters the city (becoming Picacho Avenue), and the interstate begins to turn south. Just south of the New Mexico State University campus, I-10 has a junction with the southern terminus of I-25. At the I-25 junction, I-10/US 180 also becomes concurrent with US 85. At this point, the highway is now headed almost due south before crossing into Anthony, Texas (in El Paso County, Texas) from Anthony, New Mexico (in Doña Ana County).

State Road 14
Location	Arizona–New Mexico state line to Road Forks
Length	5 mi (8.0 km)
Existed	1927–1960

I-10 replaced US 80 through New Mexico, bypassing major portions of old US 80 in the western portion of the state and in Doña Ana County. US 80 was one of the original United States Numbered Highways established in 1926. The portion of US 80 between the Arizona state line and Anthony was decommissioned on October 6, 1989, while the remainder of the route through the state was removed October 12, 1991.

From 1927 to 1960, the section of I-10 between Road Forks and the Arizona state line was designated New Mexico State Road 14 (NM 14). Though it was only 5 miles (8 km) long, NM 14 and its Arizona counterpart, SR 86, served as a direct bypass for US 80 between Road Forks and Benson, Arizona. US 80 itself looped south to Douglas, Arizona, at the Mexico–US border between Road Forks and Benson. By the late 1940s, NM 14 had been paved and carried the majority of US 80 traffic by 1950. With the advent of I-10, NM 14 was removed from the state road system in 1960.

The interstate was first numbered I-10 by the American Association of State Highway Officials, in cooperation with the Department of Commerce, in 1957.

County	Location	mi	km	Exit	Destinations	Notes
Hidalgo	​	0.000	0.000		I-10 west – Tucson	Continuation into Arizona
	​	3.630	5.842	3	Steins
	​	5.833	9.387	5	NM 80 south – Road Forks	Former US 80 west
	​	11.200	18.025	11	NM 338 south – Animas
	​	15.680	25.235	15	Gary
	Lordsburg	20.820	33.507	20	New Mexico Information Center / Rest Area I-10 BL east (W. Motel Drive)	Free maps, literature & Internet service
		22.610	36.387	22	NM 494 (Main Street)
		24.565– 24.610	39.534– 39.606	24	I-10 BL / US 70 west (E. Motel Drive)	Western end of US 70 overlap; former US 80 west
	​	29.556	47.566	29	Ulmorris	This does not show on sign
	​	34.273	55.157	34	NM 113 south – Playas
Grant	​	42.570	68.510	42	Separ
	​	49.900	80.306	49	NM 146 south – Hachita, Antelope Wells
Luna	​	56.210	90.461	55	Quincy
	​	63.320	101.904	62	Gage
	​	68.570	110.353	68	NM 418 east	Former US 70 / US 80
	Deming	81.220	130.711	81	I-10 BL east (W. Pine Street)
		82.120	132.159	82A	US 180 west to NM 26 east / I-25 – Silver City, Hatch	Western end of US 180 overlap
		82.580	132.900	82B	Cedar Street Railroad Boulevard	Eastbound signage Westbound signage
		85.240	137.180	85	I-10 BL west (E. Pine Street)
	​	102.950	165.682	102	Akela
Doña Ana	​	116.125	186.885	116	NM 549 west	Former US 70 / US 80
	​	127.230	204.757	127	Corralitos Road
	Las Cruces	132.031	212.483	132	Las Cruces International Airport
		134.637	216.677	135	US 70 east (W. Picacho Avenue)	Eastern end of US 70 overlap
		138.968	223.647	139	NM 292 south (Motel Boulevard)
		140.215	225.654	140	NM 28 (Avenida de Mesilla)
		141.552– 141.827	227.806– 228.248	142	NM 478 (Main Street) / NM 101 west (University Avenue) / Valley Drive ( NM 188)	Valley Drive not signed eastbound; NM 478 (Main Street) not signed westbound; NM 478 is former US 80/US 85
		144.349– 144.650	232.307– 232.792	144	I-25 north (US 85) – Las Cruces, Albuquerque	Western end of US 85 overlap; southern terminus of I-25
	​	151.200	243.333	151	NM 228 – Mesquite
	​	154.950	249.368	155	NM 227 west – Vado, Berino
	​	160.400	258.139	162	NM 404 – Anthony, Chaparral
	​	164.264	264.357		I-10 east / US 180 east / US 85 south – El Paso	Continuation into Anthony, Texas
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Concurrency terminus

• Business routes of Interstate 10
• U.S. Roads portal

• Media related to Interstate 10 in New Mexico at Wikimedia Commons

Interstate 10
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