Interstate 275 (I-275) is an 83.71-mile-long (134.72 km) highway in Ohio, Indiana, and Kentucky that forms a complete beltway around the Cincinnati metropolitan area and includes a part in a state (Indiana) not entered by the parent route. It had been the only auxiliary Interstate that enters three states, but that changed in July 2018 when I-295 in Delaware and New Jersey was extended into Pennsylvania. It is the longest beltway with an Interstate highway designation in the United States, enclosing an area of over 250,000 acres (100,000 ha). It is also the third longest beltway overall in the United States; only the Sam Houston Tollway and the Grand Parkway, both encircling Greater Houston, are longer. For a short distance in northwest Hamilton County, it overlaps with I-74 and US Route 52 (US 52). It is also concurrent with US 52 very briefly in southern Hamilton County as well.

I-275 is also known as the Cincinnati Bypass and officially known as the Donald H. Rolf Circle Freeway in Ohio, after a state senator, but locals rarely use these names, instead simply referring to it as "275" or "the loop". In 2011, Kentucky named its segment the Ronald Reagan Highway, not to be confused with Ronald Reagan Cross County Highway across the river in Cincinnati. The section in Clermont County is also designated as the Staff Sergeant Matt Maupin Veterans Memorial Highway.

This section does not cite any sources. Please help improve this section by adding citations to reliable sources. Unsourced material may be challenged and removed. (November 2023) (Learn how and when to remove this message)

I-275 heads west toward Indiana, passing by Cincinnati/Northern Kentucky International Airport, with Kentucky Route 212 (KY 212) used as the service road to and from the airport. Then, near Hebron, west of the airport, I-275 has an interchange with KY 237, before passing over the Ohio River into Indiana.

In Indiana, I-275 passes through a rural area with only one interchange at US 50/State Road 1 (SR 1). I-275 heads northeast toward Ohio; at the Ohio state line, I-275 passes over US 50.

I-275 heads northeast toward Springdale, and I-275 runs concurrently with I-74 and US 52. When the concurrency ends, I-275 has an intersection with State Route 126 (SR 126, Ronald Reagan Cross County Highway). Then, I-275 has interchanges with US 27 and US 127. I-275 turns east, having an interchange with SR 4, SR 747, I-75, and US 42. I-275 turns southeast, having an interchange with I-71 and US 22/SR 3. I-275 passes over the Little Miami River, entering Clermont County, where it is officially named in honor of Keith Matthew Maupin, a local soldier killed during the Iraq War. I-275 turns due south toward Milford and connects with SR 28, SR 450, SR 32, and SR 125. I-275 turns due west toward Kentucky, passing through a short concurrency with US 52, before crossing over the Ohio River into Kentucky.

From Ohio, I-275 heads southwest toward Highland Heights. I-275 has an interchange with I-471 near Highland Heights. I-275 turns due west toward Crestview Hills, passing through an interchange with KY 9, KY 16, and KY 17. In Crestview Hills, I-275 has an interchange with US 25/US 42/US 127. I-275 turns northwest toward I-71/I-75.

This section needs expansion with: how the highway was built and its precursors. You can help by adding to it. (August 2012)

On May 20, 2008, a tractor-trailer hauling a locomotive separated while traveling on the ramp from westbound I-74 to southbound I-275. After the trailer detached, it crashed into supports for the bridge on I-74 eastbound going over the ramps between I-275 and I-74 westbound. As a result, the Ohio Department of Transportation (ODOT) shut down eastbound I-74 for several weeks. Both ramps between I-74 west and I-275 were closed as well because of fears the bridge would collapse, but two crossovers were built so that traffic could use one lane of westbound I-74 to travel east around the damaged bridge.

State	County	Location	mi	km	Exit	Destinations	Notes
Kentucky	Kenton	Erlanger	83.780 0.000	134.831 0.000	84	I-71 / I-75 – Louisville, Lexington, Cincinnati	I-71/75 exit 185
	Boone	​	2.027	3.262	2	Mineola Pike
		​	3.969	6.387	4	KY 212 to KY 20 – Cincinnati/Northern Kentucky International Airport	Signed as exits 4A (east) and 4B (west) westbound
		Hebron	7.028	11.310	6	KY 237 (North Bend Road) – Hebron	Signed as exits 6A (north) and 6B (south) westbound; former exit 8; exit 7 until 2001
					8	Graves Road	Opened in November 2020
		Idlewild	11.427	18.390	11	KY 3608 to KY 20 – Petersburg	I-275 west becomes north inner; I-275 south becomes east outer
Ohio River			13.858	22.302	Carroll Lee Cropper Bridge; Kentucky–Indiana state line
Indiana	Dearborn	Lawrenceburg Township	15.13	24.35	16	SR 1 north to US 50 – Lawrenceburg, Greendale, Aurora, Brookville	Southern terminus of SR 1; access to Hollywood Casino Lawrenceburg, Rising Star Casino and Belterra Casino
			17.02	27.39	Indiana–Ohio state line
Ohio	Hamilton	Whitewater Township	20.99	33.78	21	Kilby Road – Harrison
			24.24	39.01	25	I-74 west / US 52 west – Indianapolis	South end of I-74 / US 52 overlap; I-74 exit 5
			27.02	43.48	27	SR 128 (Hamilton–Cleves Road) – Hamilton, Cleves	I-275 north becomes east inner; I-275 west becomes south outer
		Colerain Township	27.82	44.77	28	I-74 east / US 52 east – Cincinnati	East end of I-74 / US 52 overlap; I-74 exit 9
			30.47– 30.91	49.04– 49.74	31	Ronald Reagan Cross County Highway east / Blue Rock Road	Complete access formed by two partial interchanges: eastbound exit and westbound entrance at Ronald Reagan Cross County Highway; westbound exit and eastbound, westbound entrances at Blue Rock Road
			33.04	53.17	33	US 27 / SR 126 (Colerain Avenue) – Oxford	Access to Northgate Mall
		Colerain Township–Springfield Township– Forest Park tripoint	36.40– 37.05	58.58– 59.63	36	US 127 (Hamilton Avenue) – Forest Park, Fairfield
		Forest Park	38.25	61.56	39	Winton Road – Fairfield, Greenhills	Access to Forest Fair Village; westbound exit is split into separate north and south exits attached via collector/distributor lane
		Springdale	40.40	65.02	41	SR 4 (Dixie Highway) – Springdale, Fairfield, Hamilton
			41.40	66.63	42	SR 747 (Princeton Pike) – Springdale, Glendale	Signed as exits 42A (south) and 42B (north) westbound; access to Tri-County Mall
		Sharonville	42.74	68.78	43	I-75 (Millcreek Expressway) – Dayton, Cincinnati	Signed as exits 43A (south) and 43B (north); I-75 exit 16
			43.47	69.96	44	Mosteller Road – Sharonville
			45.36	73.00	46	US 42 (Lebanon Road) – Sharonville, West Chester, Mason
			46.81	75.33	47	Reed Hartman Highway – Sharonville, Blue Ash
		Montgomery	48.24	77.63	49	I-71 – Columbus, Cincinnati	I-71 north exit 17, south exits 17A-B; signed as exits 49A (south) & 49B (north) westbound
		Sycamore Township–Montgomery line	49.22	79.21	50	US 22 / SR 3 (Montgomery Road) – Montgomery, Morrow
		Symmes Township	51.86	83.46	52	Loveland–Madeira Road – Loveland, Indian Hill, Madeira
	Clermont	Miami Township	54.30	87.39	54	Wards Corner Road	I-275 east becomes south inner; I-275 north becomes west outer
			57.31	92.23	57	SR 28 – Milford, Blanchester
		Union Township	59.20	95.27	59	SR 450 (Milford Parkway) to US 50 – Milford, Hillsboro	Signed as exits 59A (west) and 59B (east); southbound exit uses collector/distributor lane
			63.42	102.06	63	SR 32 – Newtown, Batavia	Access to Eastgate Mall
			65.91	106.07	65	SR 125 (Ohio Pike) – Amelia	I-275 south becomes west inner; I-275 east becomes north outer
	Hamilton	Anderson Township	68.83	110.77	69	Five Mile Road
			70.95	114.18	71	US 52 east (Kellogg Avenue) – New Richmond	East end of US 52 overlap
		Cincinnati	72.64	116.90	72	US 52 west (Kellogg Avenue) – Cincinnati	West end of US 52 overlap; access to Belterra Park
Ohio River			73.061	117.580	Combs–Hehl Bridge; Ohio–Kentucky state line
Kentucky	Campbell	Highland Heights	74.857	120.471	74	I-471 north / KY 471 south to US 27 – Cincinnati, Alexandria, Highland Heights	Southern terminus of I-471, exits 1A-B; northern terminus of KY-471; signed as exits 74A (south) and 74B (north)
		Highland Heights–Wilder line	75.454	121.431	76	Three Mile Road – Wilder, Northern Kentucky University	Access to Northern Kentucky University; eastbound exit and westbound entrance
		Wilder	77.097	124.076	77	AA Hwy (KY 9) – Wilder, Maysville, Alexandria
	Kenton	Taylor Mill	78.779	126.783	79	KY 16 (Taylor Mill Road) – Covington, Taylor Mill
		Fort Wright	79.970	128.699	80	KY 17 (Madison Pike) – Covington, Independence
		Crestview Hills	82.030	132.014	82	KY 1303 (Turkeyfoot Road) – Lakeside Park, Crestview Hills,	Access to Thomas More University; leads to Edgewood
			82.503	132.776	83	US 25 / US 42 / US 127 (Dixie Highway) – Erlanger, Florence
		Erlanger	83.780 0.000	134.831 0.000	84	I-71 / I-75 – Louisville, Lexington, Cincinnati
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Concurrency terminus       Incomplete access

• Geographic data related to I-275 at OpenStreetMap
• I-275 on Cincinnati-Transit.net