Interstate 29 (I-29) is a north–south Interstate Highway in the Midwestern United States that begins in Missouri. It travels through the Kansas City and St. Joseph metropolitan areas before exiting the state and entering Iowa. Almost all of I-29 in Missouri lies in an area called the Platte Purchase that was not originally part of Missouri when the state entered the Union in 1821.

I-29 begins at I-70 in Kansas City in a concurrency with I-35 and U.S. Route 71 (US 71) at the Downtown Loop. It crosses over the Missouri River via the Bond Bridge. I-29 and I-35 separate in northern Kansas City, with I-29 turning northwest with US 71 running concurrent with it. It passes near Kansas City International Airport and near there is concurrent with I-435. I-29 then exits the Kansas City area. It enters the eastern portion of St. Joseph while downtown St. Joseph is served by I-229, a loop of I-29. After exiting St. Joseph, US 71 separates from I-29. I-29 then passes through rural areas of northwestern Missouri on a southeast-to-northwest alignment, then crosses into Iowa north of Rock Port, approximately 55 miles (89 km) south of Council Bluffs.

I-70 east to I-435 south was alternate a via route for traffic to void the 3 at-grade crossings.

During the 2019 Midwestern US floods, I-29 in Missouri was closed to traffic in both directions from St. Joseph to Council Bluffs, Iowa when the highway got flooded. It reopened to traffic by October 2019.

County	Location	mi	km	Exit	Destinations	Notes
Jackson	Kansas City	0.000– 0.185	0.000– 0.298		I-35 south / I-70 / US 24 west / US 40 west – Wichita, Topeka	Downtown Loop; MoDOT signs this as the national southern terminus; southern end of I-35 and US 24 overlaps; I-70 exit 2G-H
				2F	Oak Street / Grand Avenue / Walnut Street	Northbound access via exit 2E; no northbound entrance; no access to this exit from I-70 westbound
				2H	Admiral Boulevard Route 9 north – North Kansas City US 24 Bus. (Independence Avenue)	Exit numbers follow I-35; former northern end of US 24 overlap; northbound exit and southbound entrance. Access to Kansas City University School of Medicine and Biosciences.
				2J	11th Street Downtown	Southbound exit and northbound entrance
				3	I-70 east / US 24 east / US 40 east / US 71 south – St. Louis, Joplin	Southern end of US 71 overlap; southbound left exit and northbound entrance; I-70 exit 2G; US 71 heads south to the Grandview Triangle; I-70 heads east to I-435 in Kansas City
		0.530	0.853	4A	The Paseo (Independence Avenue) to US 24 Bus.	Southbound exit and northbound entrance
		1.077	1.733	4B	Front Street / Grand Boulevard	Signed as exit 4 northbound
Missouri River		1.282– 1.569	2.063– 2.525	Christopher S. Bond Bridge
Clay	North Kansas City	1.616	2.601	5A	Levee Road	Southbound exit and northbound entrance; signed as exit 5 southbound
		1.668	2.684		Bedford Street	Northbound exit and southbound entrance
		2.418	3.891	5B	16th Avenue	Northbound exit and southbound entrance
		2.996– 3.015	4.822– 4.852	6	Route 210 east (Armour Road)	Access to North Kansas City Hospital
	Kansas City	4.546	7.316	8A	Parvin Road
		4.614	7.426	8B	I-35 north – Des Moines	Northern end of I-35 overlap; northbound exit and southbound left entrance; exit numbers follow I-29
		5.040	8.111	1A	Davidson Road
		5.094	8.198	1B	I-35 north – Des Moines	Southbound exit and northbound entrance; I-35 exit 8B
		6.112	9.836	1C	Route 283 south (Oak Trafficway)	Split into exits 1C (north) and 1D (south) SB; signed as "North Oak Trfwy." only NB. Access to Midwestern Baptist Seminary.
		6.584	10.596	1E	US 69 (Vivion Road)
		6.986– 7.080	11.243– 11.394	2	US 169 – Smithville	Access to Downtown Kansas City and Smithville Lake
Platte		7.890	12.698	3A	Route AA (NW Waukomis Drive)	Northbound exit and southbound entrance only
		8.284	13.332	3C	Route A (NW Gateway Drive)	Southbound exit and northbound entrance only
		8.264– 8.494	13.300– 13.670	3B	I-635 south – Kansas	I-635 exits 12A-B
		8.847	14.238	4	NW 56th Street	Northbound exit and southbound entrance only
		10.226	16.457	5	Route 45 north (NW 64th Street)
	Platte Woods	11.420	18.379	6	NW 72nd Street – Platte Woods
	Kansas City	13.019	20.952	8	To Route 9 (Northwest Barry Road) – Parkville	Access to National American University and St. Luke's North Hospital
		13.543– 13.565	21.795– 21.831	9	Route 152 – Topeka, Liberty	Signed as exits 9A (east) and 9B (west)
		15.002	24.143	10	Tiffany Springs Parkway / Ambassador Drive	Ambassador Drive not signed southbound
		16.800	27.037	12	NW 112th Street
		17.818	28.675	13	To I-435 east (Route D) – Kansas City International Airport, St. Louis
		18.466– 18.702	29.718– 30.098	14	I-435 east – St. Louis	Southern end of I-435 overlap; northbound exit is via exit 13; Southbound Exit/Northbound entrance
		19.635	31.599	15	Mexico City Avenue
	Platte City	21.499– 22.394	34.599– 36.040	17	I-435 south – Topeka	Northern end of I-435 overlap
		22.856	36.783	18	Route 92 – Platte City, Weston, Leavenworth, Smithville
		24.020	38.656	19	Route HH (Main Street)
	Fair Township	25.567	41.146	20	Route 273 north / Route 371 – Tracy, Weston
	Green Township	30.090	48.425	25	Route E / Route U – Camden Point
	Dearborn	34.626	55.725	30	Route H / Route Z – New Market, Dearborn
Buchanan	Crawford Township	40.363	64.958	35	Route DD – Faucett
	Washington Township	47.503– 48.057	76.449– 77.340	43	I-229 north – Downtown St. Joseph
	St. Joseph	48.941	78.763	44	US 169 / I-29 BL north – St. Joseph, Gower
		50.448– 50.908	81.188– 81.928	46	US 36 – St. Joseph, Cameron	Signed as exits 46A (east) and 46B (west)
		52.599	84.650	47	Route 6 (Frederick Boulevard) – Clarksdale
		55.288	88.977	50	US 169 – St. Joseph, King City
Andrew	Jefferson Township	58.363	93.926	53	US 59 south / I-29 BL south / US 71 Bus. north – St. Joseph, Savannah	Southern end of US 59 overlap
		61.369– 61.921	98.764– 99.652	56	I-229 south / US 59 north / US 71 north – Maryville	Northern end of US 59 and US 71 overlaps; signed as exits 56A (north) and 56B (south)
	Lincoln Township	64.774	104.244	60	Route CC / Route K – Amazonia
	Jackson Township	69.954	112.580	65	US 59 south / Route RA / Lewis and Clark Trail – Fillmore, Savannah	Southern end of US 59 overlap
Holt	Nodaway Township	72.187	116.174	67	US 59 north / Lewis and Clark Trail – Oregon	Northern end of US 59 overlap
	Hickory Township	80.321	129.264	75	US 59 – Oregon
	Benton Township	83.844	134.934	79	US 159 – Rulo
	Mound City	88.804	142.916	84	Route 118 – Mound City
	Union Township	96.924	155.984	92	US 59 – Craig, Fairfax
Holt–Atchison county line	Lincoln–Clark township line	103.902	167.214	99	Route W – Corning
Atchison	Clay Township	112.453	180.976	107	Route 111 – Langdon, Rock Port
	Rock Port	115.410	185.734	110	US 136 – Rock Port
	Nishnabotna Township	120.636	194.145	116	Route A / Route B – Watson
		128.710	207.139		I-29 north / Lewis and Clark Trail – Council Bluffs	Continuation into Iowa
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Concurrency terminus       Incomplete access

I-29 has one auxiliary route in Missouri:

• I-229: A bypass around the west side of St. Joseph

• Interstate-Guide.com, Interstate 29 Archived 2012-05-14 at the Wayback Machine

Interstate 29
Previous state: Terminus	Missouri	Next state: Iowa