Samtgemeinde Isenbüttel is a Samtgemeinde in the district of Gifhorn, in Lower Saxony, Germany. It is situated approximately 4 km southeast of Gifhorn. 15,502 citizens are living in the Samtgemeinde Isenbüttel.

The Samtgemeinde is made up of the following village administrations Calberlah, Isenbüttel, Ribbesbüttel und Wasbüttel. The administration office is in Isenbüttel

The 4 member communities with their associated villages and smaller villages

Village	Population (Main Office) (31. Dez 2005)	Area (in km²)	Density (in Population./km²)	Villages
Gemeinde Calberlah	5.221	27,64	189	Allenbüttel, Allerbüttel, Brunsbüttel, Calberlah, Edesbüttel, Jelpke, Wettmershagen
Gemeinde Isenbüttel	6.212	18,65	333	Bornsiek, Isenbüttel, Tankumsee
Gemeinde Ribbesbüttel	2.138	24,51	187	Ausbüttel, Ribbesbüttel, Vollbüttel
Gemeinde Wasbüttel	1.962	24,51	80	Wasbüttel