Isle-aux-Grues (French for "island of cranes") is an island situated on the Saint Lawrence River, in the municipality of Saint-Antoine-de-l'Isle-aux-Grues, in the Montmagny Regional County Municipality (MRC), in administrative region of Chaudière-Appalaches, in Quebec, in Canada.

The Isle-aux-Grues is measuring about 7 kilometres long and 2 kilometres wide. However, its dimensions increase to 10 kilometres (6.2 mi) by 4 kilometres (2.5 mi), if including the flats which connect it to Île aux Oies. It is one of the twenty-one islands which make up the Isle-aux-Grues archipelago.

The island has an airstrip which is the only access to the island during the winter. Isle-aux-Grues is also served by a ferry during the summer.

Children from Isle-aux-Grues attend school in Montmagny, Quebec, travelling by plane each day.

• The Québecois painter Jean-Paul Riopelle died on the island on 12 March 2002.

On May 19, 2010 at about 3:30 p.m. Eastern time, a Cessna 172 airplane carrying four people crashed on Isle-aux-Grues, killing three people initially. The fourth later died in hospital.

The toponym "Île aux Grues" was made official on December 5, 1968 at the Commission de toponymie du Québec.

• Tourism website