The Jackson House is a historic house at 125 Jackson Street in Newton, Massachusetts. The 2+1⁄2-story timber-frame house was built either c. 1768 or c. 1782, and is one of Newton's few surviving 18th-century farmhouses. A house is known to have been on the property c. 1768, but the present house use construction methods and styling more common to a later period in the 18th century, suggesting a c. 1782 construction date. It was restyled in the 1850s to give it Greek Revival features.

The house was listed on the National Register of Historic Places in 1986.

• National Register of Historic Places listings in Newton, Massachusetts