At the 17th century, Krzysztof Radziwiłł, who was a notable magnate of Kėdainiai, created a new settlement at the western side of Kėdainiai. It was named after his son Janusz Radziwiłł. The settlement had a marketplace and a Lutheran church. Januszowo was mainly a German settlement settled by immigrants from Prussia and Saxony. For a period between 1648 and 1795, it was de facto a distinct city with its own coat of arms and a seal.
Under the Russian Empire, it was merged into Kėdainiai, except from the village area at the western end. This part was an okolica in the Josvainiai parish. During the Soviet times, most of Janušava village was again merged into Kėdainiai, except from a small suburban area.