The Jezzine District (Arabic: قضاء جزين) is a district in the South Governorate of Lebanon. The capital is Jezzine.

Some notable towns other than its capital Jezzine include Kfarhouna, Aichiyé, Bkassine, Kfar Falous, Jernaya and Homsiyé.

As of 2022, the religious make-up of the District's 62,120 voters were roughly 56% Maronite Catholics, 22% Shia, 14% Greek Catholic, 3% Sunni, 3% Greek Orthodox and 2% others.

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33°32′31″N 35°35′03″E / 33.5419°N 35.5842°E / 33.5419; 35.5842