Karimganj College, established in 1946, is one of the oldest undergraduate, coeducational college situated in Karimganj, Assam and is affiliated with the Assam University.

The college has total 19 departments and centres covering science and mathematics, commerce and humanities.

• Botany & Biotechnology
• Chemistry
• Computer Science
• Computer Application
• Ecology and Environmental Science
• Geology
• Mathematics
• Physics
• Statistics
• Zoology

• Commerce

• Arabic
• Bengali
• Economics
• English
• History
• Philosophy
• Political Science
• Sanskrit

The Union activities are divided into indoor and out-door sports, cultural activities, meeting and debates social service etc. Membership to the Union is compulsory. Principal is the Ex-officio President of the Union. Other office bearers and Class Representatives are elected annually from amongst the student who act under supervision of professors-in-charge of different sections. Students Union election is conducted as per the constitution of the Karimganj College students’ union adopted after DHE's guideline No. PC/HE/ CC, 13/2006/16 dt. 18-09-2006 based on the direction of the Hon’ble Supreme Court.

In 2024, NSUI defeat ABVP in colleges student union election. Assam Congress's Bhupen bora had campaigned for NSUI in that election. After defeated by NSUI, ABVP sat on a dharna stating the result were manipulated and demanded a recounting, but no any step was taken by authorities, resulting in boycott of oath taking ceremony by ABVP.

• Kripanath Mallah, MP of Karimganj
• Krishnendu Paul, MLA of Patharkandi
• Mission Ranjan Das, MP of Rajya Sabha
• Kamalakhya Dey Purkayastha, MLA of Karimganj North
• Zubeen Garg, Bollywood Singer
• Rajib Das, Vocalist at Dohar
• Bijoy Malakar, MLA of Ratabari
• Dr. Himadri Sekhar Das, Assam University, Silchar
• Dr. Debasish Guha Thakurata, Srikishan Sarda College, Hailakandi
• Siddique Ahmed, MLA of Karimganj South
• Radheyshyam Biswas, Former MP of Karimganj
• Dr. Manash Das
• Abu Saleh Najmuddin, Former Minister of Assam

• http://www.karimganjcollege.ac.in/