Interstate 10 (I-10) is the major east–west Interstate Highway in the Southern United States. In the U.S. state of Texas, it runs east from Anthony, at the border with New Mexico, through El Paso, San Antonio, and Houston to the border with Louisiana in Orange. At just under 880 mi (1,420 km), the Texas segment of I-10, maintained by the Texas Department of Transportation, is the longest continuous untolled freeway in North America that is operated by a single authority. It is also the longest stretch of Interstate Highway with a single designation within a single state. Mile marker 880 and its corresponding exit number in Orange, Texas, are the highest-numbered mile marker and exit on any freeway in North America. Since widening was completed in 2008, a portion of the highway west of Houston is now also believed to be the widest in the world, at 26 lanes when including feeders.

More than a third of I-10's length is located in Texas alone. El Paso, near the New Mexico state line, is 785 mi (1,263 km) from the western terminus of I-10 in Santa Monica, California, making it closer to Los Angeles than it is to Orange, Texas, 857 mi (1,379 km) away at the Louisiana state line. Likewise, Orange is only 789 mi (1,270 km) from the eastern terminus of I-10 in Jacksonville, Florida.

I-10 enters Texas northwest of El Paso near Anthony and runs southward, alongside US Route 85 (US 85) and US 180. US 85 splits off in West El Paso at exit 13 (Sunland Park Drive, Paisano Drive), where US 85 heads south on Paisano Drive, through downtown El Paso, and ends at the Stanton Street Bridge and the border with Mexico via local streets. As of the summer of 2016, the stretch of I-10 that runs through El Paso was in the midst of a major construction project, which sought to link North/South Desert Boulevard (the westside frontage roads) with Gateway East and Gateway West (the central and eastside frontage roads). Several miles of frontage road were being built where none previously existed. I-10/US 180 continues turning to the east towards downtown El Paso. I-10 then meets I-110 and US 54 (the "Patriot Freeway", or North–South Freeway) in a complex, three-level interchange referred to by locals as the "Spaghetti Bowl". I-10 and US 180 diverge east of downtown at exit 23B (Paisano Drive) as US 180 heads northeast (joining US 62 and Paisano Drive northbound) and I-10 to the southeast. I-10's frontage-road system is called Desert Boulevard where it runs through West El Paso, and Gateway Boulevard where it runs through Central and East El Paso. Among these stretches of the highway. Gateway East Boulevard is the longest, extending continuously for roughly 22 mi (35 km). Continuing towards Tornillo and Fabens, I-10 turns to the southeast and runs alongside the Rio Grande and the Mexican border for approximately 60 mi (97 km).

Where I-10 leaves the Rio Grande, it runs primarily eastward. Just before entering the city of Van Horn, at the border of Hudspeth and Culberson counties, I-10 leaves the Mountain Time Zone and enters the Central Time Zone. Just east of Kent, the western terminus of I-20 intersects with I-10. I-20 heads northeast towards the Dallas–Fort Worth area, and I-10 continues to run eastward. US 67 runs alongside I-10 for a stretch; La Entrada al Pacifico trade corridor is a part of this stretch of I-10. Near Junction, I-10 begins a more southeastwardly course as it runs toward the San Antonio metropolitan area. Near Comfort, I-10 and US 87 begin to run alongside each other until they reach San Antonio.

Because I-10 crosses some of the most rural and sparsely inhabited parts of the United States, notably the Trans-Pecos Region, it has several unique features that differentiate it from other interstate highways. I-10 is one of the very few interstates that has exceptions in Interstate Highway Standards where there are at-grade intersections (roads that intersect it at a 90-degree angle, rather than crossing via an overpass or underpass with on and off ramps). These are private-access roads (mostly from large ranches), and are found over a limited stretch in western Texas.

The stretch from Kerr County to El Paso County has an 80 mph (129 km/h) speed limit, which was the highest in the nation until the opening of the 85 mph (137 km/h) southern section of Texas State Highway 130 (SH 130) on October 24, 2012.

I-10 is the busiest freeway in San Antonio, with nearly 200,000 vehicles on an average day. On the northwest side, I-10 is known as the McDermott Freeway, named after Robert F. McDermott, former dean of the United States Air Force Academy as well as CEO of San Antonio-based USAA. The highway enters the city concurrently with US 87 from the north and travels more in a north–south direction into downtown, rather than the east–west designation found on the Interstate Highway signs. The section of I-10 from Ralph Fair Road (FM 3351) to La Cantera Parkway includes HOV lanes for both directions. The northern section from Loop 1604 to downtown serves one of the fastest growing areas of the city. A majority of the region's suburban office space is located along the corridor as are the headquarters for USAA, gasoline refiner and retailer Valero, South Texas Medical Center, the University of Texas at San Antonio (UTSA), Six Flags Fiesta Texas, and the Shops at La Cantera. I-10 intersects I-410 for the first time near Balcones Heights, a suburban city within San Antonio. The construction of a four-level interchange to accommodate the growing northwest side has been completed. Heavy commercial development dominates the landscape between I-410 and Loop 1604. Inside I-410, the route is lined with light industrial and residential areas.

As I-10 heads south into downtown, it splits into an upper level with three lanes in each direction and a lower level with two lanes in each direction. It was necessary to design the freeway this way in order to accommodate the amount of traffic heading into downtown and to fit into the narrow corridor that was surrounded by existing infrastructure. I-10 meets I-35 on the northwest side of downtown and it overlaps I-35 south to form the west side of the downtown loop. The I-35 exit numbers are carried through during the concurrency. I-10 and I-35 end their concurrency at a four-level interchange on the southwest side of downtown with the junction of US 90 from the west. I-35 continues to the south and I-10 and US 90 run concurrently to the east to form the south side of the downtown loop. This section of I-10 is known as the Jose Lopez Freeway, named after the Medal of Honor recipient. A four-level interchange with I-37 occurs approximately 2 mi (3.2 km) east of the interchange with I-35. I-10 heads east away from downtown through mainly residential neighborhoods on the east side of San Antonio. I-10's concurrency with US 87 ends just east of downtown where US 87 heads south towards Victoria. Leaving San Antonio, I-10 again passes I-410 and Loop 1604. I-10 is known as the 90th Infantry Division Memorial Highway on this stretch east of San Antonio. I-10 and US 90 continue their concurrency until they diverge in Seguin. They continue from there on to Houston nearly paralleling each other with short stints of overlaps along the route.

From the western suburb of Katy to downtown, I-10 is known as the Katy Freeway in Houston. This section was widened in 2008 to as many as 26 total lanes, counting the six lanes of the access (frontage/feeder) road, which feature traffic signals, and driveway access and are not limited-access and therefore not technically part of the freeway itself but are directly adjacent. Between the West Beltway and the West Loop, the Katy Freeway features a basic configuration of 14 lanes, featuring seven lanes each direction. This cross-section swells with auxiliary lanes, ramp lanes, and the inclusion of the frontage access roads, although those lanes are controlled by traffic signals. Including auxiliary lanes, ramp lanes, and the access frontage roads, the minimum lane count is 22 total lanes. In this section, the width is 24 lanes at multiple locations and up to 26 lanes east of Gessner Road (12 main lanes, eight lanes of access roads, and six mid-freeway HOT/HOV lanes). From the Fort Bend County line to I-610, there is a minimum of four main lanes in each direction. The maximum number of undivided lanes at any point on the freeway is nine in the eastbound direction approaching Antoine Drive (though this includes one exit-only lane); this is one of the widest sections of undivided highway in a single direction in the world. The widest right-of-way, 556 ft (169 m), occurs at the Katy Freeway's intersection with Bunker Hill; at that point, the expansion plans called for six main lanes plus two toll lanes in each direction along with 10 lanes on the feeder/frontage roads. While this section still features 14 through continuous lanes through the Bunker Hill interchange, when auxiliary lanes, ramp lanes, and the frontage access roads are included, the actual striping after construction delineates 29 lanes, including all 26 of the planned lanes plus an additional lane in each direction to enter or exit the toll lanes and one more turn lane on the eastbound feeder road.

Between I-610 and I-45 west of downtown, the interstate contains at least five main lanes in each direction. Before 2008, this section had traditionally been the widest section of I-10 in the Houston area and the only one with a significant portion below grade. A project completed in 2014 added one extra auxiliary lane in each direction between Shepherd Drive and Taylor Street. In addition, the eastbound feeder road that ends at Studemont was extended to Taylor Street. As I-10 travels through downtown, it junctions with I-45 and I-69/US 59. Both interchanges feature left exits, allowing several lane shifts for through traffic. I-10 provides access to Minute Maid Park, home of the Houston Astros, and also runs through the campus of the University of Houston–Downtown.

The section east of downtown Houston is officially known as the "East Freeway", although it is widely known by locals as the Baytown East Freeway or colloquially shortened to the Beast, due to a marketing push by Baytown, one of the largest cities in the Greater Houston Area. I-10 reaches Beaumont at an interchange with US 69/US 96/US 287 and it runs concurrently with the US Highways for 2.63 mi (4.23 km) and curves to the east again at a second interchange. At College Street (US 90), I-10 expands to eight lanes. I-10 meets US 90 again near the recently reconstructed Purple Heart Memorial Bridge over the Neches River; these highways travel concurrently the remainder of the way across the state. I-10 reaches Orange County and passes through the towns of Rose City, Vidor, Pinehurst, and Orange. Business US 90-Y splits off and comes back to I-10 near the Sabine River Bridge over the Sabine River. At the river, I-10 finally leaves Texas and crosses into Louisiana.

I-10 replaced and runs concurrently with US 85 from the New Mexico state line up until the two diverge at mile marker 13. The two highways parallel each other for several miles until US 85 continues to head south to the border with Mexico and I-10 turns east towards Downtown El Paso. Prior to the Interstate Highway system, US 85 ran concurrent with US 80 from the New Mexico border until the two diverged in Downtown El Paso. When I-10 was constructed in downtown El Paso, several blocks were demolished, and a sub-grade trench was built for the freeway. A series of overpasses now carry the preexisting north–south surface streets over the east–west stretch of I-10 through downtown. I-10 replaced US 80 through El Paso and to the southeast and east to the present day junction of I-10 and I-20. US 80 along this route has been completely removed from the highway system in favor of I-10.

At the junction with I-20, I-10 replaced US 290 eastward to the present day junction of I-10 and US 290 southeast of Junction. This section of US 290 was deleted from the highway system. From this point to near Comfort, I-10 replaced SH 27. SH 27 still exists along this stretch, mostly paralleling I-10 to the south. From Comfort southeast to San Antonio, I-10 directly replaced US 87.

I-10 generally follows the alignment of US 87 on the northwest side of San Antonio into downtown. A new alignment was built to the south of downtown for the freeway since it was impossible to upgrade the surface streets in downtown that US 87 and US 90 followed prior to the Interstate Highway System. Southeast of downtown, I-10 curves back to the northeast to connect with the pre-interstate alignment of US 90.

Construction of portions of I-10 were well underway and completed prior to the commissioning of the highway in 1959. The section from Culebra Road to Woodlawn Avenue opened as the first freeway in San Antonio in 1949, but was signed as US 87. Expansion and construction continued in the 1950s, but the bulk of the construction occurred in the 1960s after the interstate was commissioned. The $11 million project to construct the interchange with I-37 was at the time the largest single contract in the history of the state highway commission. The current alignment was completed by 1968.

Rapid growth in San Antonio led to the original highway quickly becoming inadequate, with the result that it has been in perpetual construction and expansion. In the 1980s, the portion just northwest of downtown was reconstructed to add a double deck feature to expand the freeway to five lanes in each direction. In 1990, the interstate had only two lanes in each direction from Loop 1604 to where the double-deck freeway begins near downtown. Recent construction has expanded the freeway to five lanes in each direction from just outside the I-410 loop all the way into downtown. The I-10/I-410 interchange was reconstructed into a four-level stack interchange that was completed in 2009, and a new stack interchange is being constructed at I-10/Loop 1604, expected to be completed by 2027.

When constructed during the 1960s, I-10 between Katy and Houston, known as the Katy Freeway, was built with six to eight lanes wide barring side lanes, being modest by Houston standards because existing traffic demand to the farming area of West Houston was relatively low. As the population and economic activity increased in the area, vehicular traffic increased, reaching an annual average daily traffic (AADT) of 238,000 vehicles just west of the West Loop in 2001.

In 2000, increased traffic levels and congestion led to plans being approved for widening of the freeway to 16 lanes with a capacity for 200,000 cars per day. An old railway running along the north side of the freeway was demolished in 2002 in preparation for construction which began in 2004. The interior two lanes in each direction between SH 6 and west I-610, the Katy Freeway Managed Lanes or Katy Tollway, were built as high-occupancy toll lanes and are managed by the Harris County Toll Road Authority. The section just west of SH 6 to the Fort Bend–Harris county line opened in late June 2006. Two intersections were rebuilt (Beltway 8 and I-610), toll booths were added, together with landscaping as part of Houston's Highway Beautification Project. Most of the section between Beltway 8 and SH 6 had been laid by September 2006 and work was completed in October 2008.

Tolls on the managed lanes vary by vehicle occupancy, axle count and time of day. High occupancy vehicles may travel for free at certain times.

Severe flooding of the Sabine River occurred in March 2016. Days of continuous heavy rains, coupled with the controversial opening of the Toledo Bend Dam and the release of 207,000 to 208,000 cu ft/s (5,900 to 5,900 m/s) into the river, caused the closing of I-10. The water level in Deweyville rose to 130-year record heights, prompting a joint decision by the Texas Department of Transportation (TxDOT) and the Louisiana Department of Transportation and Development (LaDOTD) to close I-10 for four days near Orange.

Much of I-10 between Houston and Beaumont was shut down in late August 2017 as Hurricane Harvey inundated the Houston and East Texas area with record rainfall. In 2020, I-10 between Beaumont and the Louisiana state line was shut down due to debris and heavy rain caused by Hurricanes Delta and Laura.

County	Location	mi	km	Exit	Destinations	Notes
El Paso	Anthony	0.000	0.000		I-10 west (US 85 north / US 180 west) – Las Cruces	Continuation into New Mexico
		0.007– 1.612	0.011– 2.594	0	FM 1905 – Anthony
		0.644– 2.020	1.036– 3.251	Tourist Info Center; exit 1 (eastbound)
	Canutillo	2.657– 3.434	4.276– 5.526	2	Spur 37 (Vinton Road) / Westway Drive
	El Paso	4.881– 5.196	7.855– 8.362	5	Check Station	Eastbound only
		5.858– 6.679	9.428– 10.749	6A	Loop 375 east (Transmountain Road) / Spur 16 south	Signed as exit 6 eastbound
		6.922	11.140	6B	Loop 375 east (Transmountain Road)	Westbound exit and eastbound entrance; Loop 375 exit 11B westbound to I-10 westbound; counterclockwise terminus of Loop 375
		7.573– 8.451	12.188– 13.601	8	SH 178 (Artcraft Road) / Paseo del Norte
		8.782– 10.241	14.133– 16.481	9	Redd Road
		10.821– 11.422	17.415– 18.382	11	SH 20 (Mesa Street) / Thorn Avenue	Thorn Avenue not signed eastbound
		12.642– 12.749	20.345– 20.518	12	Resler Drive	Closed; former westbound exit and eastbound entrance now part of US 85/SH Loop 375
		12.025– 14.525	19.352– 23.376	13	US 85 / Loop 375 (Paisano Drive) / Sunland Park Drive / Resler Drive	Eastern end of US 85 concurrency; clockwise terminus of SH 375 Loop (Loop 375); US 85 (Paisano Drive) not signed westbound; Resler Drive not signed eastbound
		15.826– 16.271	25.469– 26.186	16	Executive Center Boulevard
		17.689– 18.335	28.468– 29.507	18A	Schuster Avenue, University Avenue – University of Texas at El Paso
		18.444– 18.815	29.683– 30.280	18B	Porfirio Díaz Street, Franklin Avenue	No westbound entrance
		19.029– 19.792	30.624– 31.852	19A	SH 20 (Mesa Street) – Downtown El Paso, Convention Center, Tourist Information, Arts District	Signed as exit 19 eastbound; eastbound traffic enter Downtown via Wyoming Avenue
		19.922	32.061	19B	Downtown El Paso, Convention Center, Tourist Information, Arts District	Westbound exit only; downtown access via Missouri Avenue
		20.108– 21.940	32.361– 35.309	20	Dallas Street, Cotton Street
		20.938– 21.923	33.696– 35.282	21	Piedras Street
		21.536– 22.463	34.659– 36.151	22A	Loop 478 (Copia Street)
		21.847– 23.058	35.159– 37.108	22B	US 54 east (Patriot Freeway) / I-110 south – Alamogordo, Fort Bliss, Juárez	US 54 exit 21; I-110 exit 21A
		22.657– 23.365	36.463– 37.602	23A	Raynolds Street
		23.254– 24.001	37.424– 38.626	23B	US 62 / US 180 east (Paisano Drive) / Chelsea Street	Eastern end of US 180 concurrency
		23.787– 24.980	38.281– 40.201	24	Geronimo Drive, Trowbridge Drive	Signed as exits 24A (Trowbridge) and 24B (Geronimo) eastbound
		25.369– 26.520	40.827– 42.680	25	Airway Boulevard – El Paso Airport
		25.790– 27.326	41.505– 43.977	26	Hawkins Boulevard
					Gateway Boulevard West	Westbound entrance only
		26.793	43.119	27	Hunter Drive, Viscount Boulevard	Eastbound exit and westbound entrance; westbound access is via exit 28A
		27.811– 28.463	44.757– 45.807	28A	FM 2316 (McRae Boulevard) / Sumac Drive / Viscount Boulevard	Access to Del Sol Medical Center-East; Sumac Drive not signed westobund, Viscount Boulevard not signed eastbound
		28.717– 29.316	46.216– 47.180	28B	Yarbrough Drive, Sumac Drive
		29.660	47.733	29	Lomaland Drive	Eastbound exit and westbound entrance; westbound access is via exit 30
		30.047– 31.546	48.356– 50.768	30	Lee Trevino Drive, Lomaland Drive	Lomaland Drive not signed eastbound
		31.487– 32.937	50.673– 53.007	32	FM 659 (Zaragoza Road, George Dieter Road)
		33.800	54.396	33	Don Haskins Drive	Westbound exit only
		33.218– 34.395	53.459– 55.353	34	Loop 375 / Americas Avenue, Joe Battle Boulevard	Signed as exits 34A (Loop 375) and 34B (Americas Avenue, Joe Battle Boulevard)
	Socorro	34.970– 35.868	56.279– 57.724	35	Eastlake Boulevard
		36.847– 38.464	59.299– 61.902	37	FM 1281 (Horizon Boulevard) – Horizon City, Socorro
	Clint	42.438– 43.068	68.297– 69.311	42	FM 1110 – Clint, San Elizario
	Fabens	49.206– 49.595	79.189– 79.815	49	FM 793 – Fabens
	​	50.302– 50.993	80.953– 82.065		El Paso County Safety Rest Area	there is no exit number for this exit
	Tornillo	55.215– 55.671	88.860– 89.594	55	Tornillo
Hudspeth	Fort Hancock	68.1	109.6	68	Acala Road
		72.3	116.4	72	Spur 148 – Fort Hancock
		78.4	126.2	78	SH 20 west – McNary
	​	81.6	131.3	81	FM 2217
	​	85.1	137.0	85	Esperanza Road
	​	87.6	141.0	87	FM 34
	​	95.4	153.5	95	Frontage Road	Eastbound exit and entrance
	​	98.9	159.2	99	Lasca Road
	Sierra Blanca	105.6	169.9	105	I-10 BL east (El Paso Street)	Signed as exit 106 westbound
		106.9	172.0	107	RM 1111 (Sierra Blanca Avenue)
		108.5	174.6	108	I-10 BL west – Sierra Blanca	Westbound exit only
	Allamoore	128.9	207.4	129	Allamore
	​	132.7	213.6	133	Frontage Road	Westbound exit and entrance
Culberson	Van Horn	137.8	221.8	138	I-10 BL east / Golf Course Drive
		139.7	224.8	140A	US 90 / SH 54 (Van Horn Drive) – Valentine, Marfa, Alpine	Access to Culberson County Airport
		140.6	226.3	140B	I-10 BL west (Ross Drive)
	Wild Horse	146.3	235.4	146	Wild Horse Road
	Michigan Flat	152.9	246.1	153	Michigan Flat
	Plateau	159.4	256.5	159	Plateau
	Boracho	166.0	267.2	166	Boracho Station
	​	172.6	277.8	173	Hurds Draw Road
	Kent	176.3	283.7	176	SH 118 / RM 2424 – Kent, Fort Davis
Jeff Davis	​	181.1	291.5	181	Cherry Creek Road
	​	183.6	295.5	184	Springhills
Reeves	​	186.2	299.7	186	I-10 east – San Antonio	Westbound left exit and eastbound left entrance; provides access to I-10 east for travelers coming from I-20 west
		186.8	300.6	187	I-20 east – Fort Worth, Dallas	No eastbound entrance; left exit eastbound; no exit number eastbound; Fort Worth not signed westbound; western terminus of I-20
	​	187.6	301.9	188	Giffin Road
	​	192.3	309.5	192	FM 3078 east – Toyahvale, Fort Davis
	Balmorhea	206.0	331.5	206	I-10 BL east / FM 2903 – Toyah, Balmorhea
		209.0	336.4	209	I-10 BL west / SH 17 south – Balmorhea, Fort Davis	Western end of SH 17 concurrency
	Saragosa	211.5	340.4	212	SH 17 / FM 2448 – Pecos	Eastern end of SH 17 concurrency
	​	213.8	344.1	214	FM 2448	Westbound exit and eastbound entrance
	​	221.7	356.8	222	Hoefs Road
Pecos	​	229.1	368.7	229	Hovey Road
	​	235.2	378.5	235	Mendel Road
	​	240.8	387.5	241	Kennedy Road
	​	245.9	395.7	246	Firestone Road
	​	248.1	399.3	248	US 67 south / FM 1776 – Alpine, Marfa, Presidio, Sul Ross State University	Western end of US 67 concurrency
	​	252.3	406.0	253	FM 2037
	Fort Stockton	256.2	412.3	256	I-10 BL east – Fort Stockton
		257.0	413.6	257	US 285 – Pecos, Sanderson	No westbound entrance, access to Fort Stockton-Pecos County Airport
		258.5	416.0	259B	SH 18 – Monahans	Signed as exit 259 eastbound, access to Pecos County Memorial Hospital
		259.3	417.3	259A	FM 1053	Eastbound access is via exit 259
		260.8	419.7	261	I-10 BL west / US 385 south – Fort Stockton, Marathon	Western end of US 385 concurrency
	​	263.8	424.5	264	Warnock Road
	​	271.5	436.9	272	University Road
	​	272.6	438.7	273	US 67 north / US 385 north – San Angelo, McCamey	Eastern end of US 67/US 385 concurrency; no eastbound entrance
	​	276.6	445.1	277	RM 2023
	​	284.4	457.7	285	McKenzie Road
	​	287.5	462.7	288	Ligon Road
	Bakersfield	294.1	473.3	294	FM 11 – Bakersfield
	​	298.4	480.2	298	RM 2886
	​	306.8	493.7	307	US 190 to FM 305 – Iraan, McCamey
	​	314.3	505.8	314	Frontage Road
	​	319.9	514.8	320
	​	324.8	522.7	325	SH 290 / SH 349 – Iraan, Sheffield
Crockett	​	327.8	527.5	328	County Road 307
	​	336.7	541.9	337	County Road 305
	​	343.1	552.2	343	SH 290 west – Sheffield
	​	349.5	562.5	350	RM 2398 (County Road 405)
	​	360.8	580.7	361	RM 2083
	Ozona	363.4	584.8	363	Loop 466 / RM 2398 – Ozona
		365.2	587.7	365	SH 163 – Sterling City, Comstock	Access to Ozona Municipal Airport
		367.5	591.4	368	Loop 466 – Ozona
	​	371.8	598.4	372	Taylor Box Road
Sutton	​	380.9	613.0	381	RM 1312	Eastbound exit and westbound entrance
	​	387.3	623.3	388		Westbound exit and eastbound entrance
	​	391.8	630.5	392	RM 1989 (Caverns of Sonora Road) to RM 1312
	Sonora	399.3	642.6	399	Loop 467 – Sonora	Eastbound exit and westbound entrance
		400.0	643.7	400	US 277 – San Angelo, Del Rio	Access to Sonora Municipal Airport
		403.8	649.9	404	Loop 467 / RM 864 / RM 3130 – Sonora, Fort McKavett
	​	411.8	662.7	412	RM 3307 / County Road 305	Formerly signed "To RM 3130 / Allison Road "
	​	420.0	675.9	420	RM 3130 / County Road 306
	​	428.4	689.4	429	County Road 306 to RM 3130	Formerly signed "To RM 3130 / Harrell Road"
Kimble	Roosevelt	436.9	703.1	437	Loop 291 east – Roosevelt	Eastbound exit and westbound entrance
		438.2	705.2	438	Loop 291 – Roosevelt	Westbound exit and eastbound entrance
	​	440.7	709.2	442	Loop 291 west to RM 1674 – Fort McKavett	Loop 291 not signed westbound
	​	444.8	715.8	445	RM 1674	Eastbound exit and westbound entrance
	​	451.1	726.0	451	RM 2291 (Cleo Road)
	Junction	455.4	732.9	456	US 83 north / US 377 to Loop 481 – Junction, Menard	Western end of US 83 concurrency, access to Kimble Hospital
		457.3	736.0	457	FM 2169 (Martinez Street) – Junction
		459.8	740.0	460	Loop 481 – Junction, Texas Tech University Center at Junction	Westbound exit and eastbound entrance
	​	461.5	742.7	462	US 83 south – Leakey	Eastern end of US 83 concurrency
	Segovia	464.5	747.5	465	FM 2169 – Segovia
	​	471.3	758.5	472	RM 479 / FM 2169 / Old Segovia Road
	​	475.6	765.4	476	Stapp Ranch Road	Eastbound exit and westbound entrance
	​	476.6	767.0	477	US 290 east – Fredericksburg
Kerr	​	483.9	778.8	484	Midway Road
	Mountain Home	487.5	784.6	488	SH 27 – Mountain Home, Ingram
		489.8	788.3	490	SH 41 – Mountain Home, Rocksprings
	​	491.8	791.5	492	RM 479
Gillespie	No major junctions
Kerr	​	501.1	806.4	501	FM 1338
	Kerrville	504.8	812.4	505	RM 783 – Harper, Kerrville
		507.7	817.1	508	SH 16 – Kerrville	Access to Peterson Regional Medical Center, Kerrville VA Medical Center
	​	519.5	836.1	520	FM 1341
Kendall	Comfort			522	North Creek Road	Westbound exit and eastbound entrance
		522.4	840.7	523	US 87 north / Bus. US 87 south – San Angelo, Comfort, Fredericksburg	Western end of US 87 concurrency
		524.0	843.3	524	Bus. US 87 north / FM 1621 – Comfort, Waring
	​	526.6	847.5	527	FM 1621 / FM 289 – Waring	Eastbound access is via exit 524
	​	532.7	857.3	533	FM 289 – Welfare
	Boerne	536.9	864.1	537	Bus. US 87 south – Boerne	Business Route
		537.6	865.2	538	Ranger Creek Road	Westbound exit and eastbound entrance
		538.7	867.0	539	Johns Road
		540.1	869.2	540	SH 46 – New Braunfels, Bandera	Access to Boerne-Methodist Hospital
		541.8	871.9	542	Bus. US 87 north – Boerne	Westbound exit and eastbound entrance
		542.8	873.6	543	Boerne Stage Road, Cascade Caverns Road
Bexar	Fair Oaks Ranch	544.6	876.4	545	Balcones Creek Road, Dietz Elkhorn Road
		546.1	878.9	546	Fair Oaks Parkway, Tarpon Drive
		548.2	882.2	548	Old Fredericksburg Road, Buckskin Drive
	Leon Springs	549.5	884.3	550	FM 3351 (Ralph Fair Road)
	San Antonio	550.6	886.1	551	Boerne Stage Road – Leon Springs	Eastbound access is via exit 550
		552.9	889.8	552	Dominion Drive
		553.8	891.3	554	Camp Bullis Road
		553.9	891.4	555	La Cantera Parkway – Fiesta Texas
		555.3	893.7	556A	Loop 1604 (Anderson Loop)
		555.8	894.5	556B	Frontage Road	Access to Via Park and Ride
		557.0	896.4	557	UTSA Boulevard – University of Texas at San Antonio	Former Spur 53
		557.4	897.0	558	De Zavala Road
		558.3	898.5	559	Spur 345 south (Fredericksburg Road)	Eastbound exit and westbound entrance; access to South Texas Medical Center
		558.9	899.5	560A	Huebner Road	Signed as exit 560 westbound; access to South Texas Medical Center
		559.8	900.9	560B	Frontage Road	Eastbound exit and entrance
		560.3	901.7	561	Wurzbach Road	Access to South Texas Medical Center
		561.3	903.3	562	Medical Drive	Westbound access is via exit 561; access to South Texas Medical Center
		562.7	905.6	563	Callaghan Road	Eastbound access is via exit 562
		562.8	905.7	564	I-410 (Connally Loop)	I-410 exit 16; access to San Antonio International Airport
		563.0	906.1	565A	Crossroads Boulevard – Balcones Heights	Access to Methodist Texan Hospital
		564.3	908.2	565B	Vance Jackson Road
		565.2	909.6	566A	West Avenue
		566.0	910.9	566B	Fresno Drive
		566.2	911.2	566C	Hildebrand Avenue, Fulton Avenue	Signed as exit 567A westbound
		567.3	913.0	567	Loop 345 (Fredericksburg Road) / Woodlawn Avenue	Signed as exit 567B westbound; westbound exit via lower level
		568.1	914.3	568A	Cincinnati Avenue	Westbound exit via lower level and eastbound entrance via lower level
		568.5	914.9	568B	Spur 421 (Culebra Avenue) – Bandera	Signed as exit 568 eastbound; access via upper level
		568.7	915.2	569A	Colorado Street	Signed as exit 569 westbound; access via lower level; no eastbound entrance
		569.0	915.7	569B	Frio Street – Downtown San Antonio	Eastbound exit via lower level and entrance via lower level
		569.1	915.9	569C	Santa Rosa Street – Downtown San Antonio	Eastbound exit via upper level and westbound entrance via upper level
		569.6	916.7	570	I-35 north (Pan Am Expressway) – Austin	Western end of I-35 concurrency; no exit number westbound (concurrent section uses I-35 exit numbers); I-35 exit 156 southbound
		See I-35
		572.2	920.9	572	US 90 west (Rodriguez Freeway) – Del Rio, Lackland AFB, Port San Antonio	Western end of US 90 concurrency
		572.4	921.2		I-35 south (Pan Am Expressway) – Laredo	Eastern end of I-35 concurrency; exit 153 northbound
		573.0	922.2	573	To Spur 536 (Roosevelt Avenue) / Probandt Street
		574.1	923.9	574	I-37 / US 281 (Adams Freeway) – Corpus Christi, Johnson City, Downtown San Antonio, The Alamo	I-37 exit 139, access to San Antonio Amtrak Station
		574.9	925.2	575	Pine Street, Hackberry Street
		575.1	925.5	576	New Braunfels Avenue, Gevers Street
		576.5	927.8	577	US 87 south (Roland Avenue) – Victoria	Eastern end of US 87 concurrency
		577.4	929.2	578	Pecan Valley Drive, M. L. King Drive
		578.5	931.0	579	Houston Street, Commerce Street
		579.6	932.8	580	Loop 13 (W. W. White Road)
		580.4	934.1	581	I-410 (Connally Loop) / SH 130 south	Western end of SH 130 concurrency; I-410 exit 33; undergoing conversion from cloverleaf to stack interchange.
		581.4	935.7	582	Ackerman Road – Kirby	No access from I-10 eastbound, exit is from I-410 to I-10 eastbound
		581.7	936.2	583	Foster Road
		582.6	937.6	584	Woodlake Parkway
		585.2	941.8	585	FM 1516 – Converse
		586.8	944.4	587	Loop 1604 (Anderson Loop) – Randolph AFB, Universal City
		588.6	947.3	589	Graytown Road, Pfeil Road
		591.2	951.4	591	FM 1518 – Schertz
	Converse	593.1	954.5	593	FM 2538 (Trainer Hale Road)
Guadalupe	Marion	594.8	957.2	595	Zuehl Road
		596.7	960.3	597	Santa Clara Road
		598.5	963.2	599	FM 465 – Marion
	​	600.1	965.8	600	Schwab Road
	​	601.0	967.2	601	FM 775 – New Berlin, La Vernia
	Seguin	602.9	970.3	603	US 90 east to US 90 Alt. – Seguin	Eastern end of US 90 concurrency; eastbound exit and westbound entrance
		603.8	971.7	604	FM 725 – Lake McQueeney
		604.9	973.5	605	FM 464
		606.4	975.9	607	SH 46 / FM 78 – New Braunfels, Lake McQueeney
		608.3	979.0	609	Bus. SH 123 (Austin Street)
		609.5	980.9	610	SH 123 – San Marcos, Stockdale
		611.5	984.1	612	US 90 – Seguin
		613.8	987.8	614	SH 130 Toll north – Austin, Waco	Eastern end of SH 130 concurrency
	Kingsbury	616.8	992.6	617	FM 2438 – Kingsbury
		619.2	996.5	619	Guadalupe County Safety Rest Area	Signed as exit 618 eastbound
		619.6	997.1	620	FM 1104 – Kingsbury
	​	625.2	1,006.2	625	Darst Field Road
	Luling	627.4	1,009.7	628	SH 80 – Nixon, Luling, San Marcos
Gonzales	No major junctions
Caldwell	Luling	631.6	1,016.5	632	US 183 to US 90 – Gonzales, Cuero, Luling, Lockhart, Austin
Gonzales	​	636.8	1,024.8	637	FM 794 – Harwood
	​	642.3	1,033.7	642	SH 304 – Bastrop, Gonzales
	​	649.0	1,044.5	649	SH 97 – Waelder, Gonzales
	​	652.4	1,049.9	653	US 90 – Waelder
Fayette	Flatonia	661.2	1,064.1	661	SH 95 / FM 609 – Flatonia, Smithville, La Grange, Moulton, Shiner
	​	667.6	1,074.4	668	FM 2238 – Engle
	Schulenburg	673.6	1,084.1	674	US 77 – Schulenburg, La Grange
	​	676.9	1,089.4	677	US 90
Colorado	Weimar	681.4	1,096.6	682	FM 155 – Weimar, La Grange
	​	689.1	1,109.0	689	US 90 / Hattermann Lane
	​			692	Colorado County Safety Rest Area
	​	692.5	1,114.5	693	FM 2434 to SH 71 west – Glidden, La Grange
	Columbus	693.8	1,116.6	695	SH 71 west – La Grange, Austin	Western end of SH 71 concurrency; no eastbound exit
		695.6	1,119.5	696	SH 71 east / Bus. SH 71 – Columbus, El Campo	Eastern end of SH 71 concurrency
	​	698.1	1,123.5	698	US 90 west / Alleyton Road – Columbus	Western end of US 90 concurrency
	​	699.4	1,125.6	699	FM 102 – Eagle Lake
	​	703.5	1,132.2	704	FM 949 – Bernardo, Cat Spring
	​	708.9	1,140.9	709	FM 2761 / Bernardo Road – Bernardo
Austin	​	711.3	1,144.7	713	Beckendorff Road
	Sealy	715.5	1,151.5	716	Pyka Road
		717.5	1,154.7	718	US 90 east / FM 3538	Eastern end of US 90 concurrency
		719.3	1,157.6	720	SH 36 – Sealy, Rosenberg, Bellville
		720.2	1,159.0	720A	Outlet Center Drive	Eastbound exit only
		721.5	1,161.1	721	US 90 west	Western end of US 90 concurrency; westbound exit and eastbound entrance
	San Felipe	722.2	1,162.3	723	FM 1458 – San Felipe, Frydek
	​	724.7	1,166.3	725	Mlcak Road	Eastbound access is via exit 723
	​	725.4	1,167.4	726	Chew Road	Eastbound exit and westbound entrance
Waller	​	727.8	1,171.3	729	Peach Ridge Road, Donigan Road (US 90 east)	Eastern end of US 90 concurrency; signed as exit 730 westbound
	Brookshire	731.1	1,176.6	731	FM 1489 (Koomey Road) – Simonton
		731.9	1,177.9	732	FM 359 – Brookshire, Fulshear
	​	733.9	1,181.1	734	Woods Road
	Katy	735.0	1,182.9	735	Igloo Road, Jordan Ranch Boulevard	No westbound entrance
		736.1	1,184.6	737	Pederson Road
		738.4	1,188.3	739	Cane Island Parkway
Fort Bend		739.1	1,189.5	740	FM 1463	No eastbound exit
		739.8	1,190.6	741	Pin Oak Road	Westbound access is via exit 740
Harris		741.1	1,192.7		US 90 west / Katy Mills Boulevard	Western end of US 90 concurrency; westbound exit and eastbound entrance
		741.5	1,193.3	742	Katy-Fort Bend County Road	Eastbound access is via exit 741
		741.8	1,193.8	743A	SH 99 (Frontage Road)	Signed as exit 743 westbound; access to Memorial Hermann Katy Hospital
		742.3	1,194.6	743B	SH 99 Toll north / SH 99 south (Grand Parkway)
		743.2	1,196.1	745	Mason Road
		744.6	1,198.3	746	Westgreen Boulevard
		745.5	1,199.8	747A	Fry Road
		746.5	1,201.4	747B	Greenhouse Road
	Houston	747.3	1,202.7	748	Barker–Cypress Road	Access to West Houston Airport and Methodist West Houston Hospital
		748.6	1,204.8	750	Park Ten Boulevard
		749.8	1,206.7	751	SH 6	Former FM 1960
		750.6	1,208.0	—	I-10 Toll begins (Katy Tollway)	Western end of Katy Tollway
		751.4	1,209.3	—	Addicks Park & Ride	Interchange for Katy Tollway only
		751.1	1,208.8	753A	Eldridge Parkway
		752.6	1,211.2	753B	Dairy Ashford Road
		753.3	1,212.3	754	Kirkwood Road
		754.3	1,213.9	755	Wilcrest Drive
		755.8	1,216.3	756A	Beltway 8 (Frontage Road)	Eastbound access is via exit 755
		755.1	1,215.2	756B	Sam Houston Tollway	Signed as exit 756 eastbound
		755.9	1,216.5	757	Gessner Road	Access to Memorial Hermann Memorial City Medical Center
		757.2	1,218.6	758	Bunker Hill Road
		757.9	1,219.7	759A	Blalock Road, Echo Lane	Signed as exit 759 eastbound
		758.7	1,221.0	759B	Campbell Road	Eastbound access is via exit 759
		758.8	1,221.2	760	Bingle Road, Voss Road
		759.7	1,222.6	761A	Wirt Road, Chimney Rock Road	Signed as exit 761 eastbound
		761.0	1,224.7	761B	Antoine Drive, Silber Road	Eastbound access is via exit 761
		760.7	1,224.2	—	North Post Oak Road – NW Transit Center	Eastbound exit only for Katy Tollway
		761.5	1,225.5	—	I-10 Toll ends (Katy Tollway)	Eastern end of Katy Tollway
		761.0	1,224.7	762	Silber Road, North Post Oak Road, Katy Road	Signed as exit 762B westbound; Katy Road not signed eastbound
		762.0	1,226.3	763	I-610 (West Loop Freeway)	I-610 exit 11; entrance from I-610 south includes direct entrance ramp from US 290 (Northwest Freeway)
		762.8	1,227.6	♦	US 290 (Express Lanes)	HOV/toll exit; westbound exit and eastbound entrance
		763.5	1,228.7	764	Washington Avenue, Westcott Street	During the weekends in November 2023, access is via frontage road only (all ramps closed)
		764.3	1,230.0	765A	T. C. Jester Boulevard
		764.6	1,230.5	765B	Durham Drive, Shepherd Drive, Patterson Street
		765.3	1,231.6	766	Yale Street, Heights Boulevard
		765.8	1,232.4	767A	Studemont Drive	Eastbound exit and westbound entrance
		766.5	1,233.6	767B	Taylor Street	Eastbound access only
		767.3– 767.7	1,234.8– 1,235.5	768	I-45 (North Freeway, Gulf Freeway) – Dallas, Galveston	Signed as exits 768A (north) and 768B (south); left exits eastbound; I-45 exit 48
		768.1	1,236.1	769A	Smith Street – Downtown Houston	Eastbound exit and westbound entrance, access to Houston Amtrak station
		768.5	1,236.8	769B	San Jacinto Street / Main Street	Westbound exit and eastbound entrance, access to Houston Amtrak station
		768.6	1,236.9	769C	McKee Street, Hardy Street	Eastbound exit and westbound entrance
		769.1– 769.4	1,237.7– 1,238.2	770	I-69 / US 59 (Eastex Freeway) – Victoria, Cleveland	I-69/US 59 exit 132; signed as exits 770A (south) and 770C (north)
		769.3	1,238.1	770B	Jensen Drive, Meadow Street, Gregg Street
		770.4	1,239.8	771A	Waco Street
		770.9	1,240.6	771B	Lockwood Drive	No westbound entrance
		771.5	1,241.6	772	Kress Street, Lathrop Street
		772.5	1,243.2	773A	US 90 Alt. (North Wayside Drive)
		772.9	1,243.9	773B	McCarty Drive
		773.7	1,245.1	774	Gellhorn Drive	Eastbound exit and westbound entrance
		773.9	1,245.5	775A	I-610 (East Loop Freeway)	I-610 exit 26
		774.1	1,245.8	775B	US 90 east (Crosby Freeway) – Liberty	Eastern end of US 90 concurrency; eastbound exit and westbound entrance
		775.1	1,247.4	776A	Mercury Drive – Jacinto City, Galena Park
		775.5	1,248.0	776B	John Ralston Road, Holland Avenue
		776.4	1,249.5	778A	FM 526 (Federal Road)	Westbound access is via exit 778
		777.6	1,251.4	778B	Normandy Street	Signed as exit 778 westbound
		778.5	1,252.9	779A	Westmont Street	Westbound exit only
		778.6	1,253.0	779B	Market Street Road / Uvalde Road	Signed as exit 780 eastbound; access to East Houston Regional Medical Center
	Channelview	779.6	1,254.6	780	Freeport Street	Eastbound access is via exit 779B
		780.1	1,255.4	781A	Beltway 8 (Frontage Road)	Eastbound exit and westbound entrance
		780.5	1,256.1	781	Beltway 8 (Sam Houston Parkway) to Sam Houston Tollway	Signed as exits 781B eastbound and 781A westbound; southbound Beltway 8 provides access to Sam Houston Tollway including toll bridge
		781.3	1,257.4	781B	Market Street	Westbound exit only
		781.2	1,257.2	782	Dell Dale Avenue	No westbound entrance
		782.2	1,258.8	783	Sheldon Road
		783.1	1,260.3	784	Cedar Lane, Bayou Drive
784.4		1,262.4	785	Magnolia Avenue
785.5		1,264.1	786	Monmouth Drive
Baytown	787.0	1,266.6	787	Crosby-Lynchburg Road
	787.5	1,267.4	788	Spur 330 east – Baytown	Westbound access is via exit 787
	788.5	1,269.0	789	Thompson Road
	789.2	1,270.1	790	Ellis School Road	Westbound exit only
	789.9	1,271.2	790	Wade Road	Westbound access is via exit 791
	790.6	1,272.3	791	John Martin Road
	791.5	1,273.8	792	Garth Road	Access to San Jacinto Methodist Hospital
	792.6	1,275.6	793	North Main Street
	794.1	1,278.0	795	Sjolander Road
	795.2	1,279.8	796	Frontage Road	Signed as exit 796B westbound
Chambers	Mont Belvieu	796.7	1,282.2	798	SH 146 – Mont Belvieu, Baytown, Dayton	Signed as exit 797 eastbound
		798.6	1,285.2	799	SH 99 Toll (Grand Parkway)	Access to Grand Parkway via frontage roads; northbound SH 99 Toll opened in May 2022.
		799.9	1,287.3	800	FM 3180 (Eagle Drive)
	Cove	802.4	1,291.3	803	FM 565 – Cove, Old River-Winfree
	​	804.6	1,294.9	805	Trinity River Boat Ramp Turnaround	Eastbound exit and westbound entrance
	​	805.7	1,296.6	806	Frontage Road	Westbound entrance only
	​	806.4	1,297.8	807	Wallisville
	​	809.0	1,302.0	810	FM 563 – Anahuac, Liberty
	​	810.6	1,304.5	811	Turtle Bayou Turnaround	Eastbound exit only
	​	811.2	1,305.5	813	SH 61 – Hankamer, Anahuac	Signed as exit 812 eastbound
	​	814.0	1,310.0	815	Frontage Road, Wallace Road - Rest Area	Signed as exit 814 eastbound; rest areas off each direction's respective Frontage Road
	​	816.0	1,313.2	817	FM 1724
	​	818.3	1,316.9	819	Jenkins Road
	​	821.8	1,322.6	822	FM 1410
	Winnie	826.5	1,330.1	827	FM 1406
		827.4	1,331.6	828	SH 73 / SH 124 – Winnie, Port Arthur	Eastbound exit and westbound entrance
		827.9	1,332.4	829	FM 1663 to SH 73 / SH 124 – Winnie, Galveston
				831	Brush Island Road	Exit opened in February 2022
Jefferson	​	832.3	1,339.5	833	Hamshire Road
	​	837.7	1,348.1	838	FM 365 – Fannett, Nome
	​	842.8	1,356.4	843	Smith Road
	Beaumont	844.4	1,358.9	845	FM 364 (Major Drive)	Westbound access is via exit 847
		846.1	1,361.7	847	Brooks Road	Eastbound access is via exit 845
		847.5	1,363.9	848	Walden Road
		848.6	1,365.7	849	US 69 south / US 96 south / US 287 south – Port Arthur	Western end of US 69/US 96/US 287 concurrency; access to Jack Brooks Regional Airport
		849.5	1,367.1	850	Washington Boulevard	Eastbound access is via exit 849
		850.1	1,368.1	851	US 90 (College Street) – Liberty	Western end of US 90 concurrency; access to Baptist Beaumont Hospital
		851.5	1,370.4	852A	Laurel Avenue	Westbound exit and eastbound entrance
		850.5	1,368.7	852B	Calder Avenue, Harrison Avenue, Gladys Avenue
		851.7	1,370.7	853A	US 69 north / US 96 north / US 287 north – Lufkin, Jasper	Eastern end of US 69/US 96/US 287 concurrency
		852.2	1,371.5	853B	11th Street
		852.9	1,372.6	853C	7th Street	Eastbound exit and westbound entrance
		853.4	1,373.4	854	Spur 380 (M. L. King Parkway)
		854.2	1,374.7	855A	Willow Street – Downtown Beaumont
		854.3	1,374.9	855B	Magnolia Avenue, Pine Street	Eastbound access is via exit 854
Neches River				Purple Heart Memorial Bridge
Orange	​	855.3	1,376.5	856	Old Highway 90 – Rose City	Eastbound exit and westbound entrance
	Rose City	857.3	1,379.7	858	Asher Turnaround – Rose City
		858.3	1,381.3	859	Dewitt Road, Bonner Turnaround, Asher Turnaround
	Vidor	859.5	1,383.2	860	FM 105 (N Main Street) – Vidor	Westbound access is via exit 861
		860.4	1,384.7	861	Tram Road, Old Highway	Westbound access is via exit 862B
		860.6	1,385.0	861A	SH 12 – Mauriceville, Deweyville	Westbound exit signed as exit 862B
		861.8	1,386.9	862A	Timberlane Drive, Lakeside Street	Eastbound exit only
		863.2	1,389.2	864	FM 1132 (Evangeline Drive) / FM 1135 (Kishi Road)
		864.6	1,391.4	865	Doty Road	Westbound exit only
		866.5	1,394.5	867	Frontage Road	Eastbound exit only
	​	867.7	1,396.4	869	FM 1442 – Bridge City
	​	869.2	1,398.8	870	FM 1136
	​	871.3	1,402.2	872	North Mimosa Lane, Jackson Drive	Westbound exit only
	Orange	871.8	1,403.0	873	SH 62 / SH 73 – Bridge City, Port Arthur, Mauriceville
		872.4	1,404.0	874A	Bus. US 90 east – Pinehurst	Eastbound exit and westbound entrance; eastbound entrance is via Womack Road
		873.3	1,405.4	875	Womack Road	Westbound exit and eastbound entrance
	Orange–Pinehurst line	873.5	1,405.8		FM 3247 (M. L. King Jr. Drive)	Signed eastbound as exit 874; separate westbound exit from Womack Road; access to Baptist Orange Hospital
		874.7	1,407.7		Woodlark Street	Eastbound exit and entrance only
	Orange	875.7	1,409.3	876	Frontage Road – Adams Bayou	Closed for construction; normally westbound exit only
		875.8	1,409.5	877	SH 87 (16th Street) – Orange, Newton	No westbound exit (closed for construction)
		877.1	1,411.6	878	Bus. US 90 west (Simmons Drive)
		878.7	1,414.1	879	Texas Travel Information Center	Eastbound access is via exit 880
		879.0	1,414.6	880	Sabine River Turnaround	Eastbound exit and westbound entrance
Sabine River		879.6	1,415.6	Texas–Louisiana line
					I-10 east / US 90 east – Lake Charles	Continuation into Louisiana
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Closed/former       Concurrency terminus       Electronic toll collection       HOV only       Incomplete access       Unopened

I-10 has four business loops within the state. All of these routes are in the far western Trans-Pecos region. These routes are located along the former routes of US 80 and US 290 and include Bus. I-10-C in Sierra Blanca, Bus. I-10-D in Van Horn, Bus. I-10-F in Balmorhea, and Bus. I-10-G in Fort Stockton.

I-10 has three auxiliary routes in Texas:

• I-110: A spur route in El Paso providing a connection over the Bridge of the Americas to Ciudad Juarez in Mexico
• I-410: The Connally Loop, a beltway around San Antonio
• I-610: The inner beltway around Houston

• U.S. Roads portal
• Texas portal

Interstate 10
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