Kilburn Grammar School was an English grammar school which opened in 1898 in Kilburn, north-west London. The school ceased to exist in 1967.

The school's history is detailed in a book by Richard E Brock. It was founded by the Rev. Dr. Henry George Bonavia Hunt, vicar of St Paul's, Kilburn, at a time when there was no general state provision for secondary education. The new boys' school opened in one room at 1 Willesden Lane in January 1898, then occupied two rooms at the Polytechnic Institute at Priory Park Road, before moving in 1899 to a house at 28 Cavendish Road.

In April 1900, the school began moving to new purpose-built premises at Salusbury Road. In July 1900 the Hampstead and Highgate Express reported that the school's hall was opened by Bishop Mandell Creighton. Old boys of the school became known as 'Old Creightonians'. In 1907, the school was purchased jointly by the Urban District of Willesden and Middlesex County Council to become the first state secondary school in the borough, run by the higher education committee made up of representatives of both local authorities. Fees were charged until these were abolished by the Education Act 1944 for all state schools.

In 1964, London's local government was reorganised. As a result, Middlesex County Council and the Municipal Borough of Willesden were abolished in 1965, being replaced by a new London Borough of Brent, which had sole responsibility for education. An early decision by the new authority was to close the grammar school (and others) and create a new boys' school on the premises, Kilburn Senior High School. This had a comprehensive intake at 13, and started in September 1967. While the existing (age 14+) pupils completed their traditional grammar school education, by the early 1970s only the buildings and a diminishing number of teachers who had stayed on were left. The traditions of the school including the house system, societies and its sporting name were long gone.

In 1973, KSHS merged with the girls' school Brondesbury and Kilburn High School (established in 1892) on the opposite side of the road to form Brondesbury and Kilburn High School, also comprehensive. In 1989, this school, in turn, merged with others and moved to a different site to form Queens Park Community School. The former Edwardian grammar school premises in Salusbury Road were sold by the borough in 1989 and are now occupied by the Islamia Girls' School (fee-paying) and Islamia Primary School (voluntary-aided).

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Kilburn Grammar School's old boys' association was established in 1919, and celebrated its centenary in 2019. It has around 400 members, all of whom attended or taught at the school before its closure in 1967.

51°32′22″N 0°12′30″W / 51.5395°N 0.2082°W / 51.5395; -0.2082