Kips Bay, or Kip's Bay, is a neighborhood on the east side of the New York City borough of Manhattan. It is roughly bounded by 34th Street to the north, the East River to the east, 23rd Street to the south, and Third Avenue to the west.

Kips Bay is part of Manhattan Community District 6, and its primary ZIP Codes are 10010 and 10016. It is patrolled by the 13th and 17th Precincts of the New York City Police Department.

According to The Encyclopedia of New York City and the New York City Department of City Planning, Kips Bay proper is generally bounded by East 34th Street to the north, the East River to the east, East 27th Street to the south, and Third Avenue to the west. City documents have also used New York City census tract 70 (from 29th to 34th Streets, First to Third Avenues) as an approximation for Kips Bay, and referred to tract 66, immediately below it, as "Bellevue South".

The American Guide Series defines the combined Kip's Bay–Turtle Bay area as running from 27th Street north 59th Street, and from Third Avenue to the East River, excluding the neighborhoods of Beekman Place and Sutton Place.

For its entry on Kips Bay, the American Institute of Architects' AIA Guide to New York City uses the area from 23rd Street north to roughly 38th Street, and from the East River west to just past Second Avenue. In AIA Guide, Kips Bay is adjacent to Tudor City and the United Nations/Turtle Bay area on the north, Murray Hill and Rose Hill on the west, and the Stuyvesant Square area and Peter Cooper Village on the south.

Other popular definitions of the neighborhood, such as that by The New York Times, include 23rd Street to the south, 34th Street to the north, Lexington Avenue to the west, and the East River to the east. To the north is Murray Hill; to the west is Madison Square, NoMad, and/or Rose Hill; and to the south is the Bellevue area or the Gramercy Park neighborhood and Peter Cooper Village.

Kips Bay was an inlet of the East River running from what is now 32nd Street to 37th Street. The bay extended into Manhattan Island to just west of what is now First Avenue and had two streams that drained into it. The bay was named after New Netherland Dutch settler Jacobus Hendrickson Kip (1631–1690), son of Hendrick Hendricksen Kip, whose farm ran north of present-day 30th Street along the East River. The bay became reclaimed land, yet "Kips Bay" remains the name of the area. Kip built a large brick and stone house, near the modern intersection of Second Avenue and East 35th Street. The house stood from 1655 to 1851, expanded more than once, and when it was demolished was the last farmhouse from New Amsterdam remaining in Manhattan. Iron figures fixed into the gable-end brickwork commemorated the year of its first construction. Its orchard was famous, and, when first President George Washington was presented with a specimen of its Rosa gallica during his first administration (1789–1793), when New York was serving as the first national capital city, it was claimed to have been the first garden to have grown it in the Thirteen Colonies.

Kips Bay was the site of the Landing at Kip's Bay, an episode of the American Revolutionary War (1775–1783) and part of the New York and New Jersey campaign. About 4,000 British Army troops under General William Howe landed at Kips Bay on September 15, 1776, near what is now the foot of East 33rd Street off the East River from a Royal Navy fleet which had first landed earlier on Staten Island, then Long Island for the pivotal Battle of Brooklyn (also known as the Battle of Long Island) the previous month. Howe's forces defeated about 500 American militiamen stationed at Kips Bay by Washington and commanded by Colonel William Douglas. The American forces immediately retreated, and the British occupied New York Town at the south point of the island soon afterward forcing General Washington to retreat northward to the Harlem River.

A single survivor of the late 18th or early 19th century in the neighborhood is the simple vernacular white clapboard house, much rebuilt, at 203 East 29th Street. The house, standing gable-end to the street, is one of a mere handful of wooden houses that remain on Manhattan Island. Its date of construction is unknown but has been variously dated from around 1790 to as late as 1870; currently listed on the National Register of Historic Places, the house is privately owned and not open to the public.

South of the Kips Bay Farm stood the substantial Federal-style villa erected facing the East River by Henry A. Coster, in the thirty-acre estate that was purchased in 1835 by Anson Greene Phelps; towards the city, the Bull's Head cattle market fronting the Boston Post Road extended southwards from 27th Street to 23rd Street, affording a distinctly less rural aspect; the villa was removed to make way for row houses in the 1860s and the cattle market was moved farther out of town, to 42nd Street.

The neighborhood has been rebuilt in patches, featuring both new high-rise structures often set back from the street, and a multitude of exposed party walls that were never meant to be seen in public. A nearly forgotten feature is the private alley called Broadway Alley, between 26th and 27th Streets, halfway between Lexington and Third Avenues, reputedly the last unpaved street in Manhattan; it is not known what this alley is named after, since it is not near the main Broadway.

In 1940 the Madison Square Boys (and later Girls) Club, which previously had been located on East 30th Street just east of Second Avenue, built its own facilities on East 29th Street (back-to-back with its older facility). In the 1990s, the Club sold its building to the Churchill School and Center, and moved its office in the Empire State Building.

In the 1960s and 1970s, several high-rise apartment complexes were constructed between First and Second avenues as a result of urban renewal. Located between East 30th and 33rd streets, the NYU-Bellevue urban renewal project resulted in the development of Kips Bay Towers, a 1,112-unit apartment complex designed by architect I. M. Pei and completed in 1963. The Bellevue South urban renewal project, located between 23rd and 30th streets, resulted in multiple housing developments, including East Midtown Plaza and Phipps Plaza (named after 19th century industrialist and philanthropist Henry Phipps).

Waterside Plaza is a residential and business complex built on a pier above the East River between East 25th and East 28th Streets which includes the United Nations International School. There were plans to build additional above-water apartments, offices, and a hotel in the 1980s, but environmental concerns and community opposition doomed the project. Today, the waterfront south of Waterside Plaza is Stuyvesant Cove Park. The park includes a small man-made brownfield land mass extending out into the East River, which was created from excess concrete dumped into the river when the site was a ready-mix plant.

For census purposes, the New York City government classifies Kips Bay as part of a larger neighborhood tabulation area called Murray Hill-Kips Bay. Based on data from the 2010 United States census, the population of Murray Hill-Kips Bay was 50,742, a change of 2,323 (4.6%) from the 48,419 counted in 2000. Covering an area of 334.93 acres (135.54 ha), the neighborhood had a population density of 151.5 inhabitants per acre (97,000/sq mi; 37,400/km). The racial makeup of the neighborhood was 66.6% (33,818) White, 4.8% (2,423) African American, 0.1% (55) Native American, 16.2% (8,233) Asian, 0% (16) Pacific Islander, 0.4% (181) from other races, and 2% (1,008) from two or more races. Hispanic or Latino of any race were 9.9% (5,008) of the population.

The entirety of Community District 6, which comprises Kips Bay and East Midtown, had 53,120 inhabitants as of NYC Health's 2018 Community Health Profile, with an average life expectancy of 84.8 years. This is higher than the median life expectancy of 81.2 for all New York City neighborhoods. Most inhabitants are adults: a plurality (45%) are between the ages of 25 and 44, while 22% are between 45 and 64, and 13% are 65 or older. The ratio of youth and college-aged residents was lower, at 7% and 12% respectively.

As of 2017, the median household income in Community District 6 was $112,383. In 2018, an estimated 10% of Kips Bay and East Midtown residents lived in poverty, compared to 14% in all of Manhattan and 20% in all of New York City. One in twenty-five residents (4%) were unemployed, compared to 7% in Manhattan and 9% in New York City. Rent burden, or the percentage of residents who have difficulty paying their rent, is 42% in Kips Bay and East Midtown, compared to the boroughwide and citywide rates of 45% and 51% respectively. Based on this calculation, as of 2018, Kips Bay and East Midtown are considered to be high-income relative to the rest of the city and not gentrifying.

Within Kips Bay, the area along First Avenue is dominated by the institutional buildings of New York University, including Tisch Hospital, NYU College of Dentistry, NYU School of Medicine, and Rusk Institute of Rehabilitation Medicine; Bellevue Hospital Center teaching hospital, including Hunter College's Brookdale Health Sciences Center and the Alexandria Center for the Life Sciences; and the Manhattan VA Hospital for the U.S. Department of Veterans Affairs. Further north on First Avenue, in Murray Hill between East 37th and East 38th Streets, is the former Kips Bay Brewing Company, originally constructed in 1895 and now occupied by offices.

Many businesses in the neighborhood use the neighborhood's name: e.g. Kips Bay Cinemas, Kips Bay Cleaners, Kips Bay Endoscopy Center and the Kips Bay branch of the New York Public Library.

Since 1965, the area has had a commercial strip mall on Second Avenue between East 30th and 32nd Streets, set back from the street by a driveway running parallel to Second Avenue. This group of stores is referred to as "Kips Bay Plaza".

New York City's first microapartment tower opened in Kips Bay in 2016. Named Carmel Place after its location at the intersection of East 27th Street and Mount Carmel Place, the building contains 55 units ranging in size from 260 to 360 square feet (24 to 33 m) and was constructed using modular units prefabricated at the Brooklyn Navy Yard. The project was the winner of a competition sponsored by the New York City Department of Housing Preservation and Development to design, construct and operate a microapartment building on a city-owned site and pilot the use of compact apartments to accommodate smaller households.

Kips Bay is patrolled by two precincts of the NYPD. The 13th Precinct is located at 230 East 21st Street and serves the part of the neighborhood south of 30th Street, while the 17th Precinct is located at 167 East 51st Street and serves the part of the neighborhood north of 30th Street. The 13th and 17th Precincts ranked 57th safest out of 69 patrol areas for per-capita crime in 2010. The high per-capita crime rate is attributed to the precincts' high number of property crimes. As of 2018, with a non-fatal assault rate of 35 per 100,000 people, Kips Bay and East Midtown's rate of violent crimes per capita is less than that of the city as a whole. The incarceration rate of 180 per 100,000 people is lower than that of the city as a whole.

The 13th Precinct has a lower crime rate than in the 1990s, with crimes across all categories having decreased by 80.7% between 1990 and 2018. The precinct reported 2 murders, 18 rapes, 152 robberies, 174 felony assaults, 195 burglaries, 1,376 grand larcenies, and 37 grand larcenies auto in 2018. The 17th Precinct also has a lower crime rate than in the 1990s, with crimes across all categories having decreased by 80.7% between 1990 and 2018. The precinct reported 0 murders, 13 rapes, 63 robberies, 91 felony assaults, 80 burglaries, 748 grand larcenies, and 26 grand larcenies auto in 2018.

Kips Bay is served by the New York City Fire Department (FDNY)'s Engine Company 16/Ladder Company 7 fire station, located at 234 East 29th Street.