Knoxville Center Mall, originally known as East Towne Mall, was a shopping mall located in North Knoxville, Tennessee. It was in operation from 1984 to January 2020 and was demolished in 2021.

In 1984, East Towne Mall opened along Interstate 640 in a rapidly growing area  The mall featured anchors such as Miller's, JCPenney, Sears, Profitts, and Service Merchandise, along with a junior anchor, Regal Cinemas. In 1998, Sam's Club inaugurated its southeast corner location within the mall's outlot area.

In 1997, the mall underwent a significant renovation led by Simon Property Group. The exterior was retained, but a new entrance was introduced. The interior received upgrades with new tile, paint, trim, and a distinctive Tennessee mountain theme. Following the renovation, the mall was rebranded as Knoxville Center Mall.

Miller's transitioned to Hess's in 1988. However, after being acquired by Profitts, Hess's eventually closed down. Despite Profitts operating a store at the mall at that time, they chose not to maintain a dual anchor. In 1992, they sold the anchor to Dillard's, which opened a store in place of Hess's at the mall. Service Merchandise closed in 1999 and reopened as Rush Fitness, later becoming Gold's Gym.

In 2005, Belk acquired Profiits, resulting in the store becoming Belk. On May 29, 2008, Dillard's, facing declining sales, announced closure, effective September 2008. In 2016, the mall changed ownership to Knoxville Partners LLC, By August 2017, Knoxville Partners LLC had changed the name of the mall back to East Towne Mall. Signage at the mall remained unchanged, and the mall was still marketed as Knoxville Center Mall. JCPenney closed on September 17, 2017, and Sears followed suit on September 2, 2018. By October 2019, the mall had dwindled to 12 stores, a dentist's office, an event center, and two restaurants. Belk, the largest remaining store, closed on November 16, 2019.

On October 31, 2019, the owners declared the mall's complete closure, with all leases terminating on January 31, 2020. The Regal Cinema theater unexpectedly closed the same day as the closure announcement. Despite plans to transform the mall into a mixed-use facility, including office space, retail, dining, and entertainment, the decline persisted. The mall ceased operations on January 31, 2020.

As of September 2020, property ownership was shared among the corporate parents of Dillard's and Belk, along with TF Knoxville TN LLC and Millertown Pavilion LLC.  In September 2020, Hillwood Enterprises sought rezoning for the 78-acre mall site to construct an e-commerce fulfillment center for Amazon, with an estimated redevelopment cost of $70 million. The demolition of the mall began in April 2021 and was completed later that year. The Amazon Fulfillment Center, DNA6, opened for service on the former mall site in August 2024.

• Vacant Anchor Space; September 2008 – January 31, 2020; former Dillard's (opened as Miller's, later Hess's); 123,601 sq ft or 11,482.9 m)
• Vacant Anchor Space; September 17, 2017 – January 31, 2020; former JCPenney; 133,431 sq ft or 12,396.1 m)
• Vacant Anchor Space; September 2, 2018 – January 31, 2020; former Sears; 179,628 sq ft or 16,688.0 m)
• Vacant Anchor Space; November 16, 2019 – January 31, 2020; former Belk (opened as Proffitt's); 108,048 sq ft or 10,038.0 m)

• Dillard's (closed in September, 2008)
• Miller's (closed in 1988, re-opened as Hess's)
• Hess's (closed in 1992, became Dillards)
• JCPenney (closed on September 17, 2017)
• Proffitt's (closed due to corporate realignment, reopened as Belk)
• Service Merchandise (two-story store near Sears which closed to become The Rush Fitness Complex; 54,000 sq ft or 5,000 m)
• The Rush Fitness Complex (rebranded as Gold's Gym)
• Gold's Gym (former The Rush Fitness Complex, two level store; 54,000 sq ft or 5,000 m; closed on May 16, 2018)
• Sears (closed on September 2, 2018)
• Regal Cinemas (closed on October 31, 2019; original anchor)
• Belk (closed on November 16, 2019)

East Towne Mall opened with a food court in the center of the mall located on the upper level of the Center Court. By October 2019, the food court only had one restaurant, which was a Chinese takeout. There was also a Chinese buffet on the lower level. The food court was located directly next to the 10-screen Regal Cinemas location.

• Official website (archived)

36°01′58″N 83°52′36″W / 36.03284°N 83.87662°W / 36.03284; -83.87662