The Kourou (French pronunciation: [kuru]) is a river in French Guiana, discharging into the Atlantic Ocean. It is 144 km (89 mi) long. The town of Kourou is located at its estuary, which is generally used as a pleasure port.

Like the river Amazon, it has brown, muddy waters due to sediments picked up from the forest. A great many different fish species live in the river and are used in the local diet.

Like many Guyanaise rivers, it is polluted by mercury, as a result of clandestine gold mining.