Kuopio railway station (Finnish: Kuopion rautatieasema, Swedish: Kuopio järnvägsstation) is located in the Maljalahti district of the city of Kuopio in the Northern Savonia region of Finland. The current concrete station building was completed in 1934, which replaced the original wooden station building situated 900 m (3,000 ft) to the east, which was constructed in 1889; the latter site is now a goods yard.

Asemakatu ("Station Street"), the street on which the station is situated today, was previously named Linnankatu ("Castle Street") in the early 1900s. The name Asemakatu itself was previously used for a stretch of road situated north of the rail bridge at Maaherrankatu ("Landlord Street"). The aforementioned original railway station was located at the eastern end of this Asemakatu; today, this stretch of road is named Pohjolankatu ("North Street").