La Reine (French pronunciation: [la ʁɛn]) is a municipality in northwestern Quebec, Canada, on the La Reine River in the Abitibi-Ouest Regional County Municipality. It had a population of 307 in the Canada 2021 Census.

The place is named after La Reine Regiment (French for "the Queen"), that was founded in 1634 and fought under General Montcalm at the Battle of Carillon and Battle of Quebec.

The first pioneers were from Berthier County and arrived in 1913, around the time when the National Transcontinental Railway was completed. The train station was first designed as Okiko, derived from the Algonquin name for the La Reine River Okikadosag Sibi. The following year the Mission of Saint-Philippe-de-La Reine was founded. In 1917, the place was incorporated as the United Township Municipality of La Reine-et-Desmeloizes-Partie-Ouest. In 1922, the village itself separated from the united township and formed the Village Municipality of La Reine.

In 1949, the united township municipality changed its name and status to the Municipality of La Reine. In 1981, this municipality and the village municipality were rejoined.

Historical census populations – La Reine, Quebec

Year Pop. ±% 1921 799 —     1931 948 +18.6% 1941 809 −14.7% 1951 662 −18.2% 1956 646 −2.4% 1961 572 −11.5%	Year Pop. ±% 1966 482 −15.7% 1971 356 −26.1% 1976 238 −33.1% 1981 237 −0.4% 1986 520 +119.4% 1991 473 −9.0%	Year Pop. ±% 1996 437 −7.6% 2001 386 −11.7% 2006 362 −6.2% 2011 340 −6.1% 2016 339 −0.3% 2021 307 −9.4%
Source: Statistics Canada

Canada Census Mother Tongue - La Reine, Quebec
Census		Total		French				English				French & English				Other
Year		Responses		Count	Trend	Pop %		Count	Trend	Pop %		Count	Trend	Pop %		Count	Trend	Pop %
2021		305		290	10.8%	95.1%		0	0.0%	0.0%		5	n/a%	1.6%		5	50.0%	1.6%
2016		340		325	3.0%	95.6%		0	0.0%	0.0%		0	0.0%	0.0%		10	n/a%	2.9%
2011		335		335	2.9%	100.0%		0	100.0%	0.0%		0	0.0%	0.0%		0	100.0%	0.0%
2006		365		345	6.8%	94.5%		10	n/a%	2.7%		0	0.0%	0.0%		10	0.0%	2.7%
2001		380		370	15.9%	97.4%		0	0.0%	0.0%		0	0.0%	0.0%		10	n/a%	2.6%
1996		440		440	n/a	100.0%		0	n/a	0.0%		0	n/a	0.0%		0	n/a	0.0%

Municipal council (2024):

• Mayor: Fanny Dupras-Rossier
• Councillors: Réjean Bernard, Chantal Godbout, Jean-François Royer, David Royer, Sophie Bouchard, Réal East

Notable people from La Reine include:

• Christine Moore – NDP politician

• List of municipalities in Quebec