State Route 92 (SR 92) is a state highway in the U.S. state of California, serving as a major east-west corridor in the San Francisco Bay Area. From its west end at State Route 1 in Half Moon Bay near the coast, it heads east across the San Francisco Peninsula and the San Mateo–Hayward Bridge to downtown Hayward in the East Bay at its junction with State Route 238 and State Route 185. It has interchanges with three freeways: Interstate 280 (the Junipero Serra Freeway), U.S. Route 101 (the Bayshore Freeway) in or near San Mateo, and Interstate 880 (the Nimitz Freeway) in Hayward. It also connects indirectly to Interstates 238 and 580 by way of Hayward's Foothill Boulevard, which carries Route 238 and flows directly into Route 92.

Between Half Moon Bay and Interstate 280, Route 92 winds through the Coast Range as a narrow, mainly undivided two and three lane highway with a switchback turn. The east-bound uphill portion was upgraded with a long passing lane. Between Interstate 280 and Interstate 880 it is entirely a divided multilane highway, including the toll San Mateo-Hayward Bridge, the longest span across the San Francisco Bay; west of that bridge, Route 92 is carried on twin girder bridges across Seal Slough, which forms the border between the cities of San Mateo and Foster City. East of Interstate 880 the route becomes a divided surface street in Hayward, locally known as Jackson Street.

State Route 92 traverses through significant habitat areas including wetland, California oak woodland, chaparral and grassland. In one serpentine soil location near Crystal Springs Reservoir, it passes near one of the only known colonies of the endangered wildflower Pentachaeta bellidiflora and near one of the limited number of colonies of the endangered Eriophyllum latilobum.

SR 92 is part of the California Freeway and Expressway System, and a small portion near SR 1 as well as the entire portion east of I-280 are part of the National Highway System, a network of highways that are considered essential to the country's economy, defense, and mobility by the Federal Highway Administration. SR 92 is eligible for the State Scenic Highway System, but it is not officially designated as a scenic highway by the California Department of Transportation.

• Aerial views of SR 92
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  View directed east, showing US 101 interchange, serpentine Seal Slough, and the San Mateo Bridge
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  View directed west near interchange with I-280, showing Crystal Springs Reservoir and route from San Mateo to Half Moon Bay
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  View directed east c. 1962, showing 19th Avenue Freeway segment under construction; the Antoine Borel family estate is the wooded area north (left) of the new freeway
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  View directed west as-completed c. 1963, showing full cloverleaf interchange with SR 82, center, and bridges over SP's Peninsula Corridor
• 
  View directed north over Hayward; SR 92 runs along bottom right corner

The alignment was designated as Legislative Route Number 105 by Caltrans in 1933.

The San Mateo section also was referred to as the 19th Avenue Freeway which was the street name where the freeway now exists. Parts of the street remain. This section is also known as the J. Arthur Younger Freeway; J. Arthur Younger was a United States representative who served during the 1950s and 60s. On August 29, 1963, the 19th Avenue segment was completed and by 1964, the present name had been adopted; planning began for the segments in Alameda County, east of the San Mateo–Hayward Bridge, and the remainder in San Mateo County, west of Interstate 280.

An upgrade of the intersection with Main Street in Half Moon Bay, near the western terminus, was scheduled to be completed by fall 2008.

The old cloverleaf interchange with Interstate 880 was converted into a three-level combination interchange with direct ramp replacements for two of the tight "cloverleaf" ramps, and a new wider and taller overpass to carry Route 92 over Interstate 880. The project took four years and was completed in October 2011.

A similar cloverleaf interchange at SR 82 (El Camino Real) was rebuilt in 2018 into a partial cloverleaf interchange. Two of the loop off-ramps from SR 92 were eliminated: from westbound SR 92 to northbound El Camino Real, and from eastbound SR 92 to southbound El Camino Real. The remaining off-ramps were widened and signalized to allow left and right turns onto El Camino Real.

Planning for improvements to the interchange with the Bayshore Freeway (U.S. 101) began in 2018; construction is scheduled to begin in 2024. In addition, a separated bikeway will be built on Fashion Island Boulevard, which largely follows the former alignment of 19th Avenue, connecting the cities of Foster City and San Mateo. This project is scheduled to be completed by the end of 2026.

Except where prefixed with a letter, postmiles were measured on the road as it was in 1964, based on the alignment that existed at the time, and do not necessarily reflect current mileage. R reflects a realignment in the route since then, M indicates a second realignment, L refers to an overlap due to a correction or change, and T indicates postmiles classified as temporary (for a full list of prefixes, see California postmile § Official postmile definitions). Segments that remain unconstructed or have been relinquished to local control may be omitted. The numbers reset at county lines; the start and end postmiles in each county are given in the county column.

County	Location	Postmile	Exit	Destinations	Notes
San Mateo SM 0.00-R18.80	Half Moon Bay	0.00		SR 1 – San Francisco, Santa Cruz	Western terminus
		0.20		Main Street – Downtown Half Moon Bay	Former SR 1
	​	5.19		SR 35 south (Skyline Boulevard) – Big Basin	West end of SR 35 overlap
	​	7.19		SR 35 north (Skyline Boulevard) – San Francisco	East end of SR 35 overlap
	​		Western end of freeway
	​	R7.31	8	I-280 (Junipero Serra Freeway) – San Francisco, San Jose	Signed as exits 8A (south) and 8B (north) eastbound; I-280 exit 33
	San Mateo	R7.93	9A	Ralston Avenue – Belmont	Former Legislative Route 214
		R8.67	9B	De Anza Boulevard, Polhemus Road
		R9.38	10	West Hillsdale Boulevard
		R10.56	11	Alameda de las Pulgas
		R11.21	12A	SR 82 (El Camino Real)	Formerly signed as exits 12A (south) and 12B (north)
		R11.61	12B	Delaware Street	Formerly signed as exit 12C
		R12.14	13	US 101 (Bayshore Freeway) – San Francisco, San Jose	Signed as exits 13A (south) and 13B (north); US 101 exit 414B
	Foster City	R12.78	14A	Mariners Island Boulevard, Edgewater Boulevard
		R13.61	14B	Foster City Boulevard, East Hillsdale Boulevard
San Francisco Bay		R14.44– R0.00	San Mateo–Hayward Bridge (westbound toll only)
Alameda ALA R0.00-8.22	Hayward	R4.48	24	Clawiter Road, Eden Landing Road
		R5.12	25A	Industrial Boulevard
		R5.76	25B	Hesperian Boulevard – San Lorenzo
		6.39	26	I-880 (Nimitz Freeway) – Oakland, San Jose	Signed as exits 26A (south) and 26B (north); I-880 exit 27; former SR 17
			Eastern end of freeway
		6.78		Santa Clara Street	Serves CSU East Bay
		8.22		SR 185 / SR 238 (Mission Boulevard, Foothill Boulevard) to I-580	Eastern terminus; access to SR 185 is via a left turn on A Street from SR 238 north
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Concurrency terminus       Electronic toll collection       Incomplete access

• California Roads portal
• San Francisco Bay Area portal

• Caltrans: State Route 92 highway conditions
• Caltrans Traffic Conditions Map
• California Highway Patrol Traffic Incidents
• Bay Area FasTrak – includes toll information on the San Mateo–Hayward Bridge and the other Bay Area toll facilities
• California @ AARoads.com - State Route 92
• California Highways: SR 92