The Lotilla River is a river in South Sudan. It rises in marshes on the borders of the erstwhile Eastern Equatoria and Jonglei states and flows north to join the Pibor River near Pibor, at a junction with the Kangen River. The marshes are fed by the Medikiret River, which has its origins in marshes further south.

• List of rivers of South Sudan

• Lotilla River
• sudan-map
• Map of Eastern Equatoria