The Lower Basin Historic District is a national historic district located in Lynchburg, Virginia. The district defines a commercial and industrial warehouse area located between the downtown commercial area to the south and the James River waterfront to the north. The district contains a variety of mostly late 19th- and early 20th-century, multi-story, brick warehouses and factories, two-to-three-story brick commercial buildings, and a number of structures associated with the James River and Kanawha Canal and the Norfolk and Western and Chesapeake and Ohio Railways. The district is named for a wide basin of the canal that once extended between Ninth Street and Horseford Road, and contains 60 contributing buildings, two contributing structures (a viaduct and a stone bridge), and one contributing object-a monument commemorating the site of 18th-century Lynch's Ferry.

It was listed on the National Register of Historic Places in 1987, with boundary increases in 2002 and 2023, and two additional resources added in 2008.

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