Lukačovce is a village and municipality in Humenné District in the Prešov Region of north-east Slovakia.

In historical records the village was first mentioned in 1543.

The municipality lies at an altitude of 165 metres and covers an area of 7.475 km². It has a population of about 510 people.

• Media related to Lukačovce at Wikimedia Commons
• https://web.archive.org/web/20070427022352/http://www.statistics.sk/mosmis/eng/run.html