Madhukhali (Bengali: মধুখালী) is an upazila of Faridpur District in the Division of Dhaka, Bangladesh. Mathurapur village in Madhukhali has the 16th century ancient Mathurapur Deul and one of the 15 Sugar mills in Bangladesh.

Madhukhali is located at 23°32′30″N 89°37′50″E / 23.5417°N 89.6306°E / 23.5417; 89.6306. It has 45,939 households and a total area of 230.73 km.

As of the 2011 Census of Bangladesh, Madhukhali upazila had 45,939 households and a population of 204,492. 45,649 (22.32%) were under 10 years of age. Madhukhali had an average literacy rate of 52.45%, compared to the national average of 51.8%, and a sex ratio of 1010 females per 1000 males. 13,410 (6.57%) of the population lived in urban areas.

As of the 1991 Bangladesh census, Madhukhali had a population of 165,438. Males constituted 51.29% of the population, and females 48.71%. The population aged 18 or over was 83,075. Madhukhali has an average literacy rate of 32.5% (7+ years), compared to the national average of 32.4%.

Madhukhali Upazila is divided into nine union parishads: Bagat, Dumain, Gazna, Jahapur, Kamarkhali, Madhukhali, Megchami, Nowpara, and Raipur. The union parishads are subdivided into 129 mauzas and 242 villages.

• Upazilas of Bangladesh
• Districts of Bangladesh
• Divisions of Bangladesh