Mana Pools National Park is a 219,600-hectare (543,000-acre) wildlife conservation area and national park in northern Zimbabwe. It is a region of the lower Zambezi in Zimbabwe where the floodplain turns into a broad expanse of lakes after each rainy season. As the lakes gradually dry up and recede, the region attracts many large animals in search of water, making it one of Africa's most renowned game-viewing regions.

The park was inscribed, in conjunction with the Sapi Safari Area (118,000 ha or 290,000 acres) and Chewore Safari Area (339,000 ha or 840,000 acres), as a single UNESCO World Heritage Site (for a total of 676,600 ha or 1,672,000 acres) in 1984. The Mana Pools were designated a Ramsar wetland of international importance on 3 January 2013. Mana Pools National Park is a World Heritage Site based on its pure wilderness and beauty. It is home to a wide range of mammals, over 350 bird species, and aquatic wildlife and is one of the world's wildest and best preserved natural ecological areas.

Mana means ‘four’ in Shona, in reference to the four large permanent pools formed by the meanderings of the middle Zambezi. These 2,500 square kilometres of river frontage, islands, sandbanks and pools, flanked by forests of mahogany, wild figs, ebonies and baobabs, is one of the least developed national parks in Southern Africa. It has the country's biggest concentration of hippopotami and crocodiles and large dry season mammal populations of the zebra, elephant and Cape buffalo. The area is also home to other threatened species including the lion, cheetah, Cape wild dog, and near-threatened species including leopard and the brown hyena.

When the area was inscribed by UNESCO, it was one of the most important refuges for eastern black rhinoceros populations in Africa, with about 500 animals. By 1994, poaching had reduced these to just 10 remaining rhinos, which were removed to another area for their protection.

The Zimbabwean Ministry of Mines and Mining Development stated on April 28, 2023, that Shalom Mining Corporation Pvt Ltd has filed for a permit to prospect for oil and natural gas in an area with extremely high conservation value adjacent to Mana Pools. If permitted to proceed, this construction might endanger the nearby World Heritage Site.

The area was saved from a hydro-electric scheme in the early eighties which would have seen the flooding of the area. The area's ecology is affected by the regulation of the Kariba Dam and there are concerns that another potential dam on the Zambezi River, in the Mapata Gorge, might dramatically undermine the value of the area. Recently, the area was again saved from the Mupata Gorge hydro-electric scheme, where the chosen project was the Batoka Dam instead.

The park is contiguous with Zambia's Lower Zambezi National Park on the opposite side of the Zambezi River, and the larger UNESCO area is contiguous with the Urungwe Safari Area (287,000 ha), the Dande Safari Area (52,300 ha) and the Doma Safari Area (76,400 ha).

• Chitake River
• Zambezi Escarpment

• Mana Pools - Zimbabwe Parks & Wildlife Authority

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  Bridge on the Rukomechi River near Nyakasikana Gate, Mana Pools National Park
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  Zambezi River near Mutsango Lodge, Mana Pools National Park
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  Looking across the Zambezi River to the Zambezi Escarpment, Zambia, from Mana Pools National Park
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  Island in the Zambezi River from Mana Pools National Park
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  Rukomechi River from Nyakasikana Bridge, Mana Pools National Park